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CATH Superfamily 2.70.150.10

Calcium-transporting ATPase, cytoplasmic transduction domain A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Calcium-transporting ATPase, cytoplasmic transduction domain A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Phospholipid-transporting ATPase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
P-type phospholipid transporter. [EC: 7.6.2.1]
ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • The enzyme moves phospholipids such as phosphatidylcholine, phosphatidylserine, and phosphatidylethanolamine from one membrane face to the other ('flippase').
  • Formerly EC 3.6.3.1.and EC 3.6.3.13.
 4 P98196 P98197 Q8NB49 Q9QZW0