The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zona pellucida, ZP-N domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Zona pellucida sperm-binding protein 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
11 P10761 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Receptor ligand activity GO:0048018
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P10761 (/IPI) P21754 (/IPI) P48830 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 P21754 (/IPI) P79762 (/IPI) P79762 (/IPI)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
1 P21754 (/HDA)
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
1 P21754 (/IDA)
Carbohydrate binding GO:0030246
Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
1 P10761 (/ISO)
Acrosin binding GO:0032190
Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.
1 P21754 (/IPI)
Acrosin binding GO:0032190
Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.
1 P10761 (/ISO)
Structural constituent of egg coat GO:0035804
The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
1 P10761 (/IMP)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P10761 (/ISO)
Receptor ligand activity GO:0048018
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
1 P10761 (/IDA)
Receptor ligand activity GO:0048018
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
1 P10761 (/IMP)

There are 59 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Blastocyst formation GO:0001825
The initial formation of a blastocyst from a solid ball of cells known as a morula.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of leukocyte migration GO:0002687
Any process that activates or increases the frequency, rate, or extent of leukocyte migration.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of humoral immune response GO:0002922
Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
11 P10761 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of phosphatidylinositol biosynthetic process GO:0010513
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of interferon-gamma production GO:0032729
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of interleukin-4 production GO:0032753
Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Egg coat formation GO:0035803
Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of acrosomal vesicle exocytosis GO:2000368
Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
11 P10761 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of antral ovarian follicle growth GO:2000388
Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Positive regulation of type IV hypersensitivity GO:0001809
Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.
10 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS) P97708 (/ISS)
Humoral immune response mediated by circulating immunoglobulin GO:0002455
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
10 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS) P97708 (/ISS)
Positive regulation of acrosome reaction GO:2000344
Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
10 P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS) P97708 (/ISS)
Positive regulation of ovarian follicle development GO:2000386
Any process that activates or increases the frequency, rate or extent of ovarian follicle development.
10 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS) P97708 (/ISS)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
8 P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS) P97708 (/ISS)
Negative regulation of binding of sperm to zona pellucida GO:2000360
Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.
8 P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS) P97708 (/ISS)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
7 P79762 (/ISS) P79762 (/ISS) Q2QL24 (/ISS) Q4VTT4 (/ISS) Q4VTT7 (/ISS) Q4VTT8 (/ISS) Q8QFN5 (/ISS)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
7 P79762 (/ISS) P79762 (/ISS) Q2QL24 (/ISS) Q4VTT4 (/ISS) Q4VTT7 (/ISS) Q4VTT8 (/ISS) Q8QFN5 (/ISS)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
3 P10761 (/IMP) P21754 (/IMP) P48831 (/IMP)
Positive regulation of type IV hypersensitivity GO:0001809
Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.
2 P10761 (/IDA) P42098 (/IDA)
Humoral immune response mediated by circulating immunoglobulin GO:0002455
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
2 P10761 (/IDA) P48831 (/IDA)
Positive regulation of humoral immune response GO:0002922
Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
2 O77685 (/IDA) P21754 (/IDA)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
2 P10761 (/IDA) P21754 (/IDA)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
2 P10761 (/IGI) P21754 (/IGI)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
2 P10761 (/IPI) P48830 (/IPI)
Positive regulation of acrosome reaction GO:2000344
Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
2 P10761 (/IDA) P21754 (/IDA)
Positive regulation of ovarian follicle development GO:2000386
Any process that activates or increases the frequency, rate or extent of ovarian follicle development.
2 P10761 (/IMP) P48831 (/IMP)
Blastocyst formation GO:0001825
The initial formation of a blastocyst from a solid ball of cells known as a morula.
1 P10761 (/IMP)
Positive regulation of leukocyte migration GO:0002687
Any process that activates or increases the frequency, rate, or extent of leukocyte migration.
1 P10761 (/IDA)
Positive regulation of humoral immune response GO:0002922
Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
1 P10761 (/ISO)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
1 P10761 (/ISO)
Binding of sperm to zona pellucida GO:0007339
The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
1 P21754 (/TAS)
Regulation of signaling receptor activity GO:0010469
Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.
1 P10761 (/IDA)
Regulation of signaling receptor activity GO:0010469
Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.
1 P10761 (/IMP)
Positive regulation of phosphatidylinositol biosynthetic process GO:0010513
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
1 P10761 (/IDA)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 O73670 (/IDA)
Positive regulation of interferon-gamma production GO:0032729
Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
1 P10761 (/IDA)
Positive regulation of interleukin-4 production GO:0032753
Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.
1 P10761 (/IDA)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
1 O73670 (/IDA)
Egg coat formation GO:0035803
Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
1 P10761 (/IMP)
Positive regulation of T cell proliferation GO:0042102
Any process that activates or increases the rate or extent of T cell proliferation.
1 P10761 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P10761 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P10761 (/IDA)
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 P10761 (/IMP)
Oocyte development GO:0048599
The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
1 P10761 (/IMP)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
1 P10761 (/IDA)
Positive regulation of acrosome reaction GO:2000344
Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
1 P10761 (/ISO)
Negative regulation of binding of sperm to zona pellucida GO:2000360
Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.
1 P21754 (/IDA)
Negative regulation of binding of sperm to zona pellucida GO:2000360
Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.
1 P10761 (/ISO)
Positive regulation of acrosomal vesicle exocytosis GO:2000368
Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
1 P21754 (/IDA)
Positive regulation of acrosomal vesicle exocytosis GO:2000368
Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
1 P21754 (/IMP)
Positive regulation of acrosomal vesicle exocytosis GO:2000368
Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
1 P10761 (/ISO)
Positive regulation of ovarian follicle development GO:2000386
Any process that activates or increases the frequency, rate or extent of ovarian follicle development.
1 P10761 (/IDA)
Positive regulation of antral ovarian follicle growth GO:2000388
Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.
1 P10761 (/IMP)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
23 A8W993 (/ISS) G1MVJ9 (/ISS) P10761 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS)
(13 more)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
11 A8W993 (/ISS) G1MVJ9 (/ISS) O73670 (/ISS) Q2QL21 (/ISS) Q2QL24 (/ISS) Q4VTT4 (/ISS) Q4VTT5 (/ISS) Q4VTT6 (/ISS) Q4VTT7 (/ISS) Q4VTT8 (/ISS)
(1 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P21754 (/ISS) P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS)
(1 more)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
11 A8W993 (/ISS) G1MVJ9 (/ISS) O73670 (/ISS) Q2QL21 (/ISS) Q2QL24 (/ISS) Q4VTT4 (/ISS) Q4VTT5 (/ISS) Q4VTT6 (/ISS) Q4VTT7 (/ISS) Q4VTT8 (/ISS)
(1 more)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
10 P23491 (/ISS) P23491 (/ISS) P42098 (/ISS) P48830 (/ISS) P48831 (/ISS) P48832 (/ISS) P48833 (/ISS) P53785 (/ISS) P53786 (/ISS) P97708 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
3 O73670 (/IDA) P79762 (/IDA) P79762 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 P79762 (/IDA) P79762 (/IDA)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
2 P79762 (/IDA) P79762 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
2 P10761 (/IDA) P21754 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P21754 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P21754 (/IMP)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P10761 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P10761 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 P48830 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
1 P21754 (/HDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
1 P10761 (/ISO)