The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"ntegrin, alpha v. Chain A, domain 4
".
FunFam 5: Integrin, alpha 9
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | D3ZN51 (/IPI) |
|
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
1 | D3ZN51 (/IDA) |
|
Collagen binding GO:0005518
Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
1 | B8JK39 (/ISO) |
|
Laminin binding GO:0043236
Interacting selectively and non-covalently with laminins, glycoproteins that are major constituents of the basement membrane of cells.
|
1 | D3ZN51 (/IDA) |
|
Laminin binding GO:0043236
Interacting selectively and non-covalently with laminins, glycoproteins that are major constituents of the basement membrane of cells.
|
1 | B8JK39 (/ISO) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lymphangiogenesis GO:0001946
Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.
|
1 | F1Q8T4 (/IGI) |
|
Lymphangiogenesis GO:0001946
Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.
|
1 | F1Q8T4 (/IMP) |
|
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
1 | Q13797 (/IGI) |
|
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
1 | B8JK39 (/ISO) |
|
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
1 | Q13797 (/TAS) |
|
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
1 | Q13797 (/TAS) |
|
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | B8JK39 (/IGI) |
|
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
1 | D3ZN51 (/IEP) |
|
Positive regulation of osteoclast differentiation GO:0045672
Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.
|
1 | Q91YD5 (/IMP) |
|
Positive regulation of bone resorption GO:0045780
Any process that activates or increases the frequency, rate or extent of bone resorption.
|
1 | Q91YD5 (/IMP) |
|
Cell projection morphogenesis GO:0048858
The process in which the anatomical structures of a cell projection are generated and organized.
|
1 | Q91YD5 (/IMP) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q13797 (/TAS) |
|
Integrin complex GO:0008305
A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
|
1 | Q13797 (/TAS) |
|
Basal plasma membrane GO:0009925
The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
1 | B8JK39 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | D3ZN51 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | B8JK39 (/ISO) |
|
Integrin alpha9-beta1 complex GO:0034679
An integrin complex that comprises one alpha9 subunit and one beta1 subunit.
|
1 | D3ZN51 (/IDA) |
|
Integrin alpha9-beta1 complex GO:0034679
An integrin complex that comprises one alpha9 subunit and one beta1 subunit.
|
1 | B8JK39 (/ISO) |
|
Integrin alpha9-beta1 complex GO:0034679
An integrin complex that comprises one alpha9 subunit and one beta1 subunit.
|
1 | Q91YD5 (/TAS) |
|
Alpha9-beta1 integrin-ADAM8 complex GO:0071133
A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.
|
1 | Q91YD5 (/IDA) |