The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
C2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 155: extended synaptotagmin-2 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium-dependent phospholipid binding GO:0005544
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
4 A0A0B4K6F9 (/ISS) A0A0B4KGU9 (/ISS) Q7KS16 (/ISS) Q9VC62 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Synaptic vesicle exocytosis GO:0016079
Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.
4 A0A0B4K6F9 (/ISS) A0A0B4KGU9 (/ISS) Q7KS16 (/ISS) Q9VC62 (/ISS)
Intracellular transport GO:0046907
The directed movement of substances within a cell.
4 A0A0B4K6F9 (/ISM) A0A0B4KGU9 (/ISM) Q7KS16 (/ISM) Q9VC62 (/ISM)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 A0A0B4K6F9 (/ISS) A0A0B4KGU9 (/ISS) Q7KS16 (/ISS) Q9VC62 (/ISS)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
4 A0A0B4K6F9 (/ISS) A0A0B4KGU9 (/ISS) Q7KS16 (/ISS) Q9VC62 (/ISS)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 A0A0B4K6F9 (/ISM) A0A0B4KGU9 (/ISM) Q7KS16 (/ISM) Q9VC62 (/ISM)