The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 2053: Triggering receptor expressed on myeloid cells 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
2 | Q9NP99 (/TAS) Q9NP99 (/TAS) |
|
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
2 | Q9NP99 (/IPI) Q9NP99 (/IPI) |
|
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
1 | Q9JKE2 (/ISO) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Humoral immune response GO:0006959
An immune response mediated through a body fluid.
|
2 | Q9NP99 (/TAS) Q9NP99 (/TAS) |
|
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
|
2 | Q9NP99 (/TAS) Q9NP99 (/TAS) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
2 | Q9NP99 (/TAS) Q9NP99 (/TAS) |
|
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
|
2 | Q9NP99 (/TAS) Q9NP99 (/TAS) |
|
Leukocyte migration GO:0050900
The movement of a leukocyte within or between different tissues and organs of the body.
|
2 | Q9NP99 (/TAS) Q9NP99 (/TAS) |
|
Cytokine secretion involved in immune response GO:0002374
The regulated release of cytokines from a cell that contributes to an immune response.
|
1 | Q9JKE2 (/IGI) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | Q9JKE2 (/IGI) |
|
Neutrophil chemotaxis GO:0030593
The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
|
1 | Q9JKE2 (/IGI) |
|
Cytokine metabolic process GO:0042107
The chemical reactions and pathways involving cytokines, any of a group of proteins or glycoproteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
|
1 | Q9JKE2 (/IGI) |
|
Chemokine metabolic process GO:0050755
The chemical reactions and pathways involving chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
|
1 | Q9JKE2 (/IGI) |
|
Neutrophil mediated killing of gram-negative bacterium GO:0070945
The directed killing of a gram-negative bacterium by a neutrophil.
|
1 | Q9JKE2 (/IGI) |
|
Neutrophil extravasation GO:0072672
The migration of a neutrophil from the blood vessels into the surrounding tissue.
|
1 | Q9JKE2 (/IGI) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9NP99 (/TAS) Q9NP99 (/TAS) |