The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 87: Tripartite motif-containing 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
5 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q3UUU9 (/ISO) Q8CHU6 (/ISO) |
|
Signaling pattern recognition receptor activity GO:0008329
Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
|
5 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q3UUU9 (/ISO) Q8CHU6 (/ISO) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
5 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q3UUU9 (/ISO) Q8CHU6 (/ISO) |
|
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
5 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q3UUU9 (/ISO) Q8CHU6 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
5 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q3UUU9 (/ISO) Q8CHU6 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
5 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q3UUU9 (/ISO) Q8CHU6 (/ISO) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
|
1 | P15533 (/IEP) |
|
Negative regulation of interleukin-6 production GO:0032715
Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.
|
1 | P15533 (/IMP) |
|
Negative regulation of tumor necrosis factor production GO:0032720
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
|
1 | P15533 (/IMP) |
|
Negative regulation of toll-like receptor signaling pathway GO:0034122
Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.
|
1 | P15533 (/IMP) |
|
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | P15533 (/IMP) |
|
Positive regulation of viral entry into host cell GO:0046598
Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.
|
1 | P15533 (/IDA) |
|
Protein autoubiquitination GO:0051865
The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
|
1 | P15533 (/IMP) |
|
Negative regulation of NLRP3 inflammasome complex assembly GO:1900226
Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.
|
1 | P15533 (/IMP) |
|
Negative regulation of reactive oxygen species metabolic process GO:2000378
Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.
|
1 | P15533 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
5 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q3UUU9 (/ISO) Q8CHU6 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | D3YYU4 (/ISO) D3Z3L3 (/ISO) E9PV98 (/ISO) Q3UUU9 (/ISO) Q8CHU6 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P15533 (/IDA) |