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CATH Superfamily 2.60.120.330

B-lactam Antibiotic, Isopenicillin N Synthase; Chain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
B-lactam Antibiotic, Isopenicillin N Synthase; Chain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
2
1-aminocyclopropane-1-carboxylate oxidase 1
172
3D
 1wa6X00 - 76.1
1
Protein SRG1
162 - - 90.2
4
aspartyl/asparaginyl beta-hydroxylase isoform X2
157
3D
 5apaA00 - 62.2
3
Gibberellin 20 oxidase 2
148 - - 89.6
5
1-aminocyclopropane-1-carboxylate oxidase homolog 1
143 - - 92.7
6
2-oxoglutarate-Fe
II
103 - - 92.8
7
Protein DMR6-like oxygenase 2
100 - - 92.2
9
Flavonol synthase
85
3D
 2brtA00 - 89.1
8
Jasmonate-regulated gene 21
82 - - 76.4
10
1-aminocyclopropane-1-carboxylate oxidase 1
74 - - 88.1
11
Aspartate beta-hydroxylase domain-containing protein 2
73 - - 52.6
12
Gibberellin 20 oxidase 1
69 - - 94.3
13
Gibberellin 3-beta-dioxygenase 1
66 - - 90.9
14
Gibberellin 2-beta-dioxygenase 1
63 - - 89.4
15
Protein DMR6-LIKE OXYGENASE 1
61 - - 93.5
16
Naringenin,2-oxoglutarate 3-dioxygenase
61 - - 84.3
17
2-oxoglutarate-dependent dioxygenase DAO
58 - - 95.1
18
2-oxoglutarate
2OG II
53 - - 93.9
22
Probable 2-oxoglutarate-dependent dioxygenase AOP1.2
52 - - 95.0
19
Predicted protein
52 - - 73.8
21
Gibberellin 2-beta-dioxygenase 8
52 - - 83.7
20
Lipid A hydroxylase LpxO
52 - - 2.5
23
Feruloyl CoA ortho-hydroxylase 1
49
3D
 4xaeB00 - 89.3
30
Thymine dioxygenase
43
3D
 5c3sD00 - 87.7
163
Isopenicillin N synthase
41
3D
 4bb3A00 - 0.0
24
Probable 2-oxoglutarate-dependent dioxygenase At3g49630
38 - - 75.3
25
Gibberellin 2-beta-dioxygenase 2
37 - - 89.3
26
DIBOA-glucoside dioxygenase BX6
32 - - 90.0
27
Gibberellin 2-beta-dioxygenase
31 - - 78.1
29
KAR-UP oxidoreductase 1
27 - - 63.9
28
Unplaced genomic scaffold supercont1.142, whole genome shotgun sequence
27 - - 47.9
31
2-oxoglutarate
2OG II
26 - - 71.0
32
Gibberellin 20-oxidase-like protein
25 - - 72.9
33
Clavaminate synthase-like protein
24 - - 72.0
35
Probable fatty alcohol oxidase
22 - - 58.5
34
2-oxoglutarate
2OG II
22 - - 71.3
36
Oxidoreductase, 2OG-Fe
II
22 - - 78.2
37
Blast:1-aminocyclopropane-1-carboxylate oxidase
21 - - 71.7
38
Si:dkey-10o6.2
20 - - 95.2
39
Unplaced genomic scaffold supercont1.13, whole genome shotgun sequence
20 - - 75.9
40
Chromosome 21, whole genome shotgun sequence
18 - - 90.3
42
Flavanone 3-dioxygenase 3
17 - - 82.6
41
Hyoscyamine 6-dioxygenase
17 - - 76.8
43
Os04g0407800 protein
16 - - 33.3
44
2-oxoglutarate
2OG II
15 - - 76.5
45
Oxidoreductase, 2OG-Fe
II
15 - - 83.8
46
Os09g0353700 protein
13 - - 55.4
47
Similar to oxidoreductase
13 - - 88.7
49
Probable iron/ascorbate oxidoreductase
12 - - 77.4
50
Gibberellin 2-beta-dioxygenase 7
12 - - 75.7
51
Clavaminate synthase-like protein
12 - - 86.8
48
2OG-Fe
II
12 - - 32.9
52
1-aminocyclopropane-1-carboxylate oxidase 1
11 - - 65.5
53
Unplaced genomic scaffold supercont1.31, whole genome shotgun sequence
11 - - 8.8
55
Uncharacterized protein
10 - - 17.2
54
1-aminocyclopropane-1-carboxylic acid oxidase-like protein
10 - - 73.6
56
Flavonol synthase
10 - - 11.9
58
Oxidoreductase, putative
9 - - 9.7
57
Oxidoreductase, 2OG-Fe
II
9 - - 81.9
62
2-oxoglutarate-dependent dioxygenase AOP3
8 - - 58.1
60
Os01g0830500 protein
8 - - 6.9
61
2-oxoglutarate-dependent dioxygenase AOP3
8 - - 79.0
59
1-aminocyclopropane-1-carboxylate oxidase 1
8 - - 38.5
63
Unplaced genomic scaffold supercont1.11, whole genome shotgun sequence
7 - - 11.5
64
Predicted protein
7 - - 90.3
65
Similar to oxidoreductase
6 - - 12.5
67
Probable flavonol synthase 5
6 - - 57.2
66
Os06g0176500 protein
6 - - 63.5
68
S-norcoclaurine synthase 1
5 - - 40.5
71
Predicted protein
5 - - 75.1
70
2-oxoglutarate
2OG II
5 - - 75.6
69
Probable ethylene-forming enzyme
5 - - 6.2
83
Predicted protein
4 - - 64.0
72
Oxidoreductase
4 - - 18.8
78
Clavaminate synthase-like protein
4 - - 5.0
75
Oxidoreductase, 2OG-Fe
II
4 - - 12.0
84
Predicted protein
4 - - 77.4
77
2-oxoglutarate-dependent dioxygenase DAO
4 - - 6.1
82
Uncharacterized protein
4 - - 45.9
79
Protein SRG1
4 - - 21.8
73
Uncharacterized protein
4 - - 49.6
85
1-aminocyclopropane-1-carboxylate oxidase 1
4 - - 57.6
76
Uncharacterized protein
4 - - 9.1
74
Predicted protein
4 - - 67.8
80
Uncharacterized protein
4 - - 72.2
81
Os08g0249900 protein
4 - - 16.6
89
Oxidoreductase
3 - - 6.0
93
Oxidoreductase, 2OG-Fe
II
3 - - 4.4
96
Uncharacterized protein
3 - - 32.5
86
Gibberellin 3-oxidase
3 - - 20.5
94
Oxidoreductase, 2OG-Fe
II
3 - - 4.4
88
1-aminocyclopropane-1-carboxylate oxidase-like 9
3 - - 34.4
92
Os02g0320800 protein
3 - - 7.7
95
1-aminocyclopropane-1-carboxylate oxidase 1, putative
3 - - 11.3
97
1-aminocyclopropane-1-carboxylate oxidase-like 1
3 - - 32.7
90
Gibberellin 20 oxidase 5
3 - - 6.0
87
OSJNBa0073E02.10 protein
3 - - 36.8
91
Oxidoreductase, 2og-fe
Ii
3 - - 3.6
99
Protein SRG1
2 - - 27.3
128
Leucoanthocyanidin dioxygenase
2 - - 3.0
140
Oxidoreductase, 2OG-Fe
II AFU_orthologue AFUA_5G12242
2 - - 0.7
157
Uncharacterized protein
2 - - 21.8
134
Uncharacterized protein
2 - - 0.0
116
Oxidoreductase, 2OG-Fe
II
2 - - 0.0
145
Gibberellin 2-beta-dioxygenase 8
2 - - 3.9
131
Aspartate beta-hydroxylase domain-containing 1
2 - - 8.6
112
Predicted protein
2 - - 2.8
129
Oxidoreductase, 2OG-Fe oxygenase family protein, expressed
2 - - 4.8
127
Predicted protein
2 - - 0.0
106
Fe/2-OG dependent oxidoreductase
2 - - 2.6
102
Predicted protein
2 - - 33.4
133
Uncharacterized protein
2 - - 31.1
158
Predicted protein
2 - - 33.0
109
Predicted protein
2 - - 5.5
107
Predicted protein
2 - - 1.9
143
Gibberellin 2-beta-dioxygenase 8
2 - - 10.5
141
Protein DMR6-LIKE OXYGENASE 2
2 - - 0.0
135
Putative 2-oxoacid dependent dioxygenase
2 - - 42.0
126
2OG-Fe
II
2 - - 0.0
117
2OG-Fe
II
2 - - 3.6
119
Uncharacterized protein
2 - - 0.0
122
Protein SRG1 isoform A
2 - - 0.0
152
Oxidoreductase, 2OG-Fe
II
2 - - 36.6
108
Uncharacterized protein
2 - - 3.3
156
Os05g0514600 protein
2 - - 43.5
144
2-oxoglutarate
2OG II
2 - - 0.0
118
Uncharacterized protein
2 - - 0.0
130
Uncharacterized protein
2 - - 0.0
110
Uncharacterized protein
2 - - 0.3
98
Predicted protein
2 - - 24.3
153
Uncharacterized protein
2 - - 38.7
138
Putative 2og-fe oxygenase protein
2 - - 9.8
151
Os08g0249900 protein
2 - - 37.6
124
Uncharacterized protein
2 - - 0.0
100
Os09g0353400 protein
2 - - 23.0
137
Uncharacterized protein
2 - - 19.5
139
Protein DMR6-LIKE OXYGENASE 2
2 - - 0.0
142
Putative 2-oxoglutarate-dependent dioxygenase DIN11
2 - - 0.0
146
Predicted protein
2 - - 21.8
115
Predicted protein
2 - - 0.4
121
Naringenin,2-oxoglutarate 3-dioxygenase
2 - - 0.0
154
Uncharacterized protein
2 - - 42.0
123
Putative 2-oxoglutarate-dependent dioxygenase AOP1.2
2 - - 0.0
105
Uncharacterized protein
2 - - 38.6
113
2-oxoglutarate
2OG II
2 - - 0.0
150
Uncharacterized protein
2 - - 37.8
101
Uncharacterized protein
2 - - 9.1
132
Uncharacterized protein
2 - - 0.0
103
Predicted protein
2 - - 34.9
147
Uncharacterized protein
2 - - 43.4
149
2-oxoglutarate
2OG II
2 - - 34.8
111
Steroid 16alpha-hydroxylase
2 - - 6.0
136
Uncharacterized protein
2 - - 39.1
125
Uncharacterized protein
2 - - 2.6
114
Predicted protein
2 - - 4.3
155
Uncharacterized protein
2 - - 45.5
120
Uncharacterized protein
2 - - 0.0
104
Validamycin A dioxygenase
2 - - 34.3
148
Tetraspanin
2 - - 18.2
201
Uncharacterized protein
1 - - 0.0
188
Uncharacterized protein
1 - - 0.0
213
Uncharacterized protein
1 - - 0.0
165
Predicted protein
1 - - 0.0
236
Uncharacterized protein
1 - - 0.0
194
Predicted protein
1 - - 0.0
225
Uncharacterized protein
1 - - 0.0
159
Uncharacterized protein
1 - - 0.0
211
Uncharacterized protein
1 - - 0.0
203
Uncharacterized protein
1 - - 0.0
232
Uncharacterized protein
1 - - 0.0
160
Uncharacterized protein
1 - - 0.0
187
Uncharacterized protein
1 - - 0.0
189
Flavonol synthase/flavanone 3-hydroxylase, putative, expressed
1 - - 0.0
214
Uncharacterized protein
1 - - 0.0
191
Uncharacterized protein
1 - - 0.0
176
Uncharacterized protein
1 - - 0.0
193
Uncharacterized protein
1 - - 0.0
204
Uncharacterized protein
1 - - 0.0
220
Uncharacterized protein
1 - - 0.0
172
Predicted protein
1 - - 0.0
238
Uncharacterized protein
1 - - 0.0
164
Predicted protein
1 - - 0.0
210
Uncharacterized protein
1 - - 0.0
177
Uncharacterized protein
1 - - 0.0
179
Uncharacterized protein
1 - - 0.0
182
Uncharacterized protein
1 - - 0.0
186
2-oxoglutarate
2OG II
1 - - 0.0
200
Uncharacterized protein
1 - - 0.0
224
Uncharacterized protein
1 - - 0.0
195
Uncharacterized protein
1 - - 0.0
221
Os06g0176650 protein
1 - - 0.0
215
Uncharacterized protein
1 - - 0.0
178
Uncharacterized protein
1 - - 0.0
237
Uncharacterized protein
1 - - 0.0
239
Predicted protein
1 - - 0.0
242
Uncharacterized protein
1 - - 0.0
190
Uncharacterized protein
1 - - 0.0
205
Uncharacterized protein
1 - - 0.0
161
Predicted protein
1 - - 0.0
223
Putative 2-oxoglutarate-dependent dioxygenase DIN11
1 - - 0.0
166
Sexual differentiation process protein isp7
1 - - 0.0
209
Uncharacterized protein
1 - - 0.0
207
Uncharacterized protein
1 - - 0.0
198
Os08g0392300 protein
1 - - 0.0
162
Uncharacterized protein
1 - - 0.0
170
Uncharacterized protein
1 - - 0.0
217
Uncharacterized protein
1 - - 0.0
219
Uncharacterized protein
1 - - 0.0
222
Predicted protein
1 - - 0.0
235
2-oxoglutarate
2OG II
1 - - 0.0
226
Putative 2-oxoacid dependent dioxygenase
1 - - 0.0
241
Uncharacterized protein
1 - - 0.0
184
Uncharacterized protein
1 - - 0.0
181
Uncharacterized protein
1 - - 0.0
199
Uncharacterized protein
1 - - 0.0
208
Uncharacterized protein
1 - - 0.0
197
Uncharacterized protein
1 - - 0.0
230
Probable flavonol synthase 6
1 - - 0.0
183
Uncharacterized protein
1 - - 0.0
218
Uncharacterized protein
1 - - 0.0
175
Uncharacterized protein
1 - - 0.0
240
Uncharacterized protein
1 - - 0.0
228
Oxidoreductase, 2OG-Fe
II AFU_orthologue AFUA_5G12242
1 - - 0.0
171
Os02g0630300 protein
1 - - 0.0
168
Uncharacterized protein
1 - - 0.0
196
Uncharacterized protein
1 - - 0.0
234
Uncharacterized protein
1 - - 0.0
185
Uncharacterized protein
1 - - 0.0
173
Protein DOWNY MILDEW RESISTANCE 6
1 - - 0.0
192
Os05g0149300 protein
1 - - 0.0
212
Uncharacterized protein
1 - - 0.0
229
Predicted protein
1 - - 0.0
227
Uncharacterized protein
1 - - 0.0
231
Uncharacterized protein
1 - - 0.0
216
Uncharacterized protein
1 - - 0.0
233
Os05g0514600 protein
1 - - 0.0
202
Uncharacterized protein
1 - - 0.0
174
Uncharacterized protein
1 - - 0.0
180
Uncharacterized protein
1 - - 0.0
167
Uncharacterized protein
1 - - 0.0
169
2-oxoglutarate
2OG II
1 - - 0.0
206
Uncharacterized protein
1 - - 0.0
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