The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36: Calsyntenin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O94985 (/IPI) Q9EPL2 (/IPI)
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
1 O94985 (/IDA)
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
1 Q9EPL2 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q9EPL2 (/NAS)
Kinesin binding GO:0019894
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
1 O94985 (/IPI)
Kinesin binding GO:0019894
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
1 Q9EPL2 (/ISO)
X11-like protein binding GO:0042988
Interacting selectively and non-covalently with X11-like protein, a neuron-specific adaptor protein.
1 O94985 (/IPI)
X11-like protein binding GO:0042988
Interacting selectively and non-covalently with X11-like protein, a neuron-specific adaptor protein.
1 Q9EPL2 (/ISO)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
4 A0JPF2 (/IDA) E7EYL3 (/IDA) E9QIY1 (/IDA) F1R520 (/IDA)
Establishment or maintenance of microtubule cytoskeleton polarity GO:0030951
Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.
4 A0JPF2 (/IMP) E7EYL3 (/IMP) E9QIY1 (/IMP) F1R520 (/IMP)
Regulation of collateral sprouting GO:0048670
Any process that modulates the frequency, rate or extent of collateral sprouting.
4 A0JPF2 (/IMP) E7EYL3 (/IMP) E9QIY1 (/IMP) F1R520 (/IMP)
Axonal transport GO:0098930
The directed movement of organelles or molecules along microtubules in axons.
4 A0JPF2 (/IMP) E7EYL3 (/IMP) E9QIY1 (/IMP) F1R520 (/IMP)
Axon arborization GO:0140060
The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches.
4 A0JPF2 (/IMP) E7EYL3 (/IMP) E9QIY1 (/IMP) F1R520 (/IMP)
Retrograde transport, endosome to plasma membrane GO:1990126
The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.
4 A0JPF2 (/IMP) E7EYL3 (/IMP) E9QIY1 (/IMP) F1R520 (/IMP)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
1 Q9EPL2 (/IGI)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
1 Q9EPL2 (/TAS)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 O94985 (/TAS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q9EPL2 (/NAS)
Positive regulation of synaptic transmission GO:0050806
Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
1 Q9EPL2 (/IGI)
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
1 Q9EPL2 (/IGI)
Regulation of synapse maturation GO:0090128
Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
1 Q9EPL2 (/IDA)
Regulation of synapse maturation GO:0090128
Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
1 Q9EPL2 (/IMP)
Neurotransmitter receptor transport to postsynaptic membrane GO:0098969
The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.
1 Q9EPL2 (/IDA)
Neurotransmitter receptor transport to postsynaptic membrane GO:0098969
The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.
1 Q9EPL2 (/IMP)
Vesicle-mediated transport in synapse GO:0099003
Any vesicle-mediated transport that occurs in a synapse
1 Q9EPL2 (/IDA)
Vesicle-mediated transport in synapse GO:0099003
Any vesicle-mediated transport that occurs in a synapse
1 Q9EPL2 (/IMP)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
2 Q6Q0N0 (/IDA) Q9EPL2 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q9EPL2 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q9EPL2 (/HDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q9EPL2 (/IDA)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
1 Q9EPL2 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9EPL2 (/IDA)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
1 Q9EPL2 (/IDA)
Postsynaptic endosome GO:0098845
An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse.
1 Q9EPL2 (/IDA)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 Q9EPL2 (/IMP)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 Q9EPL2 (/ISO)
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
1 Q6Q0N0 (/IDA)
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
1 Q9EPL2 (/ISO)
Integral component of postsynaptic density membrane GO:0099061
The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6Q0N0 (/IDA)
Integral component of postsynaptic density membrane GO:0099061
The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9EPL2 (/ISO)
Integral component of spine apparatus membrane GO:0099065
The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6Q0N0 (/IDA)
Integral component of spine apparatus membrane GO:0099065
The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9EPL2 (/ISO)