The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Glycine cleavage system H protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipoic acid binding GO:0031405
Interacting selectively and non-covalently with lipoic acid, 1,2-dithiolane-3-pentanoic acid.
204 P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS)
(194 more)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
11 Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS)
(1 more)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 O82179 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine decarboxylation via glycine cleavage system GO:0019464
The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.
204 P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS) P0A6T9 (/ISS)
(194 more)
Lipoate biosynthetic process GO:0009107
The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.
13 O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP)
(3 more)
Protein lipoylation GO:0009249
The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.
13 O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP) O32174 (/IMP)
(3 more)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
11 Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS) Q9KMP5 (/ISS)
(1 more)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
204 P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA)
(194 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
204 P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA) P0A6T9 (/IDA)
(194 more)
Glycine cleavage complex GO:0005960
A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T.
9 P16048 (/IDA) P16048 (/IDA) P16048 (/IDA) P16048 (/IDA) P16048 (/IDA) P16048 (/IDA) P16048 (/IDA) P16048 (/IDA) P16048 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
4 P25855 (/IDA) P25855 (/IDA) Q9LQL0 (/IDA) Q9LQL0 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 O82179 (/IDA) Q9LQL0 (/IDA) Q9LQL0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P25855 (/IDA) P25855 (/IDA)
Thylakoid GO:0009579
A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
2 P25855 (/IDA) P25855 (/IDA)