The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TonB-dependent receptor, beta-barrel domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Colicin I TonB-dependent receptor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Colicin transmembrane transporter activity GO:0042912
Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.
34 P05825 (/IDA) P05825 (/IDA) P05825 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA)
(24 more)
Siderophore transmembrane transporter activity GO:0015343
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).
31 P17315 (/IMP) P17315 (/IMP) P17315 (/IMP) P17315 (/IMP) P17315 (/IMP) P17315 (/IMP) P17315 (/IMP) P17315 (/IMP) P17315 (/IMP) P17315 (/IMP)
(21 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P05825 (/IPI) P05825 (/IPI) P05825 (/IPI)
Ferric-enterobactin transmembrane transporter activity GO:0015620
Enables the transfer of ferric-enterobactin from one side of a membrane to the other.
3 P05825 (/IDA) P05825 (/IDA) P05825 (/IDA)
Ferric-enterobactin transmembrane transporter activity GO:0015620
Enables the transfer of ferric-enterobactin from one side of a membrane to the other.
3 P05825 (/IMP) P05825 (/IMP) P05825 (/IMP)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
3 P05825 (/IPI) P05825 (/IPI) P05825 (/IPI)
Ligand-gated channel activity GO:0022834
Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
3 P05825 (/IMP) P05825 (/IMP) P05825 (/IMP)
Colicin transmembrane transporter activity GO:0042912
Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.
3 P05825 (/IMP) P05825 (/IMP) P05825 (/IMP)
Siderophore uptake transmembrane transporter activity GO:0015344
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).
2 Q05098 (/IMP) Q9I527 (/IMP)
Enterobactin transmembrane transporter activity GO:0042931
Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.
2 Q05098 (/IMP) Q9I527 (/IMP)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Iron import into cell GO:0033212
The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
31 P17315 (/IEP) P17315 (/IEP) P17315 (/IEP) P17315 (/IEP) P17315 (/IEP) P17315 (/IEP) P17315 (/IEP) P17315 (/IEP) P17315 (/IEP) P17315 (/IEP)
(21 more)
Ferric-enterobactin import into cell GO:0015685
A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors.
3 P05825 (/IDA) P05825 (/IDA) P05825 (/IDA)
Ferric-enterobactin import into cell GO:0015685
A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors.
3 P05825 (/IMP) P05825 (/IMP) P05825 (/IMP)
Siderophore-dependent iron import into cell GO:0033214
A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors.
3 P05825 (/IMP) P05825 (/IMP) P05825 (/IMP)
Colicin transport GO:0042914
The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.
3 P05825 (/IDA) P05825 (/IDA) P05825 (/IDA)
Colicin transport GO:0042914
The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.
3 P05825 (/IMP) P05825 (/IMP) P05825 (/IMP)
Siderophore transport GO:0015891
The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q05098 (/IMP) Q9I527 (/IMP)
Enterobactin transport GO:0042930
The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 Q05098 (/IMP) Q9I527 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell outer membrane GO:0009279
A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
34 P05825 (/IDA) P05825 (/IDA) P05825 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA) P17315 (/IDA)
(24 more)
Integral component of cell outer membrane GO:0045203
The component of the cell outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 P05825 (/IDA) P05825 (/IDA) P05825 (/IDA)
Outer membrane GO:0019867
The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.
1 Q05098 (/IDA)