The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CD59
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 36: Serine/threonine-protein kinase receptor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Activin-activated receptor activity GO:0017002
Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta.
3 A0A0B4KG59 (/IDA) Q24229 (/IDA) Q24468 (/IDA)
Activin binding GO:0048185
Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits.
3 A0A0B4KG59 (/IDA) Q24229 (/IDA) Q24468 (/IDA)
Transforming growth factor beta-activated receptor activity GO:0005024
Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 A0A0B4KG59 (/IGI)
Activin receptor activity, type II GO:0016362
Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.
1 A0A0B4KG59 (/IDA)
Activin receptor activity, type II GO:0016362
Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.
1 A0A0B4KG59 (/IMP)
BMP receptor activity GO:0098821
Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.
1 A0A0B4KG59 (/IDA)
BMP receptor activity GO:0098821
Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.
1 A0A0B4KG59 (/IMP)

There are 28 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
3 A0A0B4KG59 (/NAS) Q24229 (/NAS) Q24468 (/NAS)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
3 A0A0B4KG59 (/TAS) Q24229 (/TAS) Q24468 (/TAS)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Primary branching, open tracheal system GO:0007428
Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Malpighian tubule morphogenesis GO:0007443
The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Head involution GO:0008258
Movement of the anterior ectoderm to the interior of the embryo.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Germ-line stem cell division GO:0042078
The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Negative regulation of salivary gland boundary specification GO:0045705
Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.
3 A0A0B4KG59 (/TAS) Q24229 (/TAS) Q24468 (/TAS)
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
3 A0A0B4KG59 (/IMP) Q24229 (/IMP) Q24468 (/IMP)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
3 A0A0B4KG59 (/NAS) Q24229 (/NAS) Q24468 (/NAS)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
1 A0A0B4KG59 (/IGI)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
1 A0A0B4KG59 (/IGI)
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
1 A0A0B4KG59 (/IMP)
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 A0A0B4KG59 (/IDA)
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 A0A0B4KG59 (/IGI)
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 A0A0B4KG59 (/IMP)
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 A0A0B4KG59 (/IDA)
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 A0A0B4KG59 (/IGI)
Activin receptor signaling pathway GO:0032924
A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 A0A0B4KG59 (/IMP)
Wing disc pattern formation GO:0035222
The process giving rise to the pattern of cell differentiation in the wing imaginal disc.
1 A0A0B4KG59 (/IMP)
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
1 A0A0B4KG59 (/IMP)
R8 cell fate specification GO:0045464
The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
1 A0A0B4KG59 (/IMP)
Positive regulation of SMAD protein signal transduction GO:0060391
Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
1 A0A0B4KG59 (/IDA)
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 A0A0B4KG59 (/IMP)
Positive regulation of neuromuscular junction development GO:1904398
Any process that activates or increases the frequency, rate or extent of neuromuscular junction development.
1 A0A0B4KG59 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 A0A0B4KG59 (/ISM) Q24229 (/ISM) Q24468 (/ISM)
Activin receptor complex GO:0048179
A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed.
3 A0A0B4KG59 (/IPI) Q24229 (/IPI) Q24468 (/IPI)
BMP receptor complex GO:0070724
A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.
1 A0A0B4KG59 (/IPI)