The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 358: protein HEG homolog 1 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 E9Q7X6 (/IPI) Q9ULI3 (/IPI)

There are 37 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
2 E9Q7X6 (/IMP) Q6R8J2 (/IMP)
Vasculogenesis GO:0001570
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
1 E9Q7X6 (/IGI)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 E9Q7X6 (/IGI)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 E9Q7X6 (/IMP)
Endothelial cell development GO:0001885
The progression of an endothelial cell over time, from its formation to the mature structure.
1 E9Q7X6 (/IGI)
Endothelial cell morphogenesis GO:0001886
The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
1 E9Q7X6 (/IMP)
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
1 E9Q7X6 (/IGI)
Lymph vessel development GO:0001945
The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
1 E9Q7X6 (/IMP)
Lymph circulation GO:0003017
The flow of lymph through the body of an animal.
1 E9Q7X6 (/IMP)
Cardiac atrium morphogenesis GO:0003209
The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
1 E9Q7X6 (/IGI)
Cardiac atrium morphogenesis GO:0003209
The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
1 E9Q7X6 (/IMP)
Ventricular trabecula myocardium morphogenesis GO:0003222
The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.
1 E9Q7X6 (/IGI)
Ventricular septum development GO:0003281
The progression of the ventricular septum over time from its formation to the mature structure.
1 E9Q7X6 (/IMP)
Cell-cell junction assembly GO:0007043
The aggregation, arrangement and bonding together of a set of components to form a junction between cells.
1 Q6R8J2 (/IMP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 E9Q7X6 (/IGI)
Post-embryonic development GO:0009791
The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
1 E9Q7X6 (/IMP)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
1 E9Q7X6 (/IMP)
Negative regulation of Rho protein signal transduction GO:0035024
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
1 Q9ULI3 (/IMP)
Negative regulation of Rho protein signal transduction GO:0035024
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
1 E9Q7X6 (/ISO)
Negative regulation of Rho protein signal transduction GO:0035024
Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
1 E9Q7X6 (/ISS)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
1 E9Q7X6 (/IGI)
Cell-cell junction organization GO:0045216
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
1 E9Q7X6 (/IMP)
Venous blood vessel morphogenesis GO:0048845
The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.
1 E9Q7X6 (/IGI)
Regulation of body fluid levels GO:0050878
Any process that modulates the levels of body fluids.
1 E9Q7X6 (/IMP)
Cardiac muscle tissue growth GO:0055017
The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
1 E9Q7X6 (/IGI)
Pericardium development GO:0060039
The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.
1 E9Q7X6 (/IGI)
Pericardium development GO:0060039
The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.
1 E9Q7X6 (/IMP)
Positive regulation of fibroblast growth factor production GO:0090271
Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 E9Q7X6 (/IGI)
Protein localization to cell junction GO:1902414
A process in which a protein is transported to, or maintained in, a location within a cell junction.
1 Q9ULI3 (/IMP)
Protein localization to cell junction GO:1902414
A process in which a protein is transported to, or maintained in, a location within a cell junction.
1 E9Q7X6 (/ISO)
Protein localization to cell junction GO:1902414
A process in which a protein is transported to, or maintained in, a location within a cell junction.
1 E9Q7X6 (/ISS)
Negative regulation of membrane permeability GO:1905709
Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane.
1 Q9ULI3 (/IDA)
Negative regulation of membrane permeability GO:1905709
Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane.
1 E9Q7X6 (/ISO)
Negative regulation of membrane permeability GO:1905709
Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane.
1 E9Q7X6 (/ISS)
Negative regulation of Rho-dependent protein serine/threonine kinase activity GO:2000299
Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
1 Q9ULI3 (/IDA)
Negative regulation of Rho-dependent protein serine/threonine kinase activity GO:2000299
Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
1 E9Q7X6 (/ISO)
Negative regulation of Rho-dependent protein serine/threonine kinase activity GO:2000299
Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
1 E9Q7X6 (/ISS)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
2 E9Q7X6 (/IDA) Q9ULI3 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
1 E9Q7X6 (/ISO)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 E9Q7X6 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 E9Q7X6 (/IDA)