The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Mitochondrial carrier domain
".
FunFam 43: mitochondrial dicarboxylate carrier isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Dicarboxylic acid transmembrane transporter activity GO:0005310
Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
|
2 | Q9UBX3 (/TAS) Q9UBX3 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9UBX3 (/IPI) Q9UBX3 (/IPI) |
|
Phosphate ion transmembrane transporter activity GO:0015114
Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.
|
1 | O89035 (/IDA) |
|
Phosphate ion transmembrane transporter activity GO:0015114
Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.
|
1 | Q9QZD8 (/ISO) |
|
Sulfate transmembrane transporter activity GO:0015116
Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
|
1 | O89035 (/IDA) |
|
Sulfate transmembrane transporter activity GO:0015116
Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
|
1 | Q9QZD8 (/ISO) |
|
Thiosulfate transmembrane transporter activity GO:0015117
Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other.
|
1 | O89035 (/IDA) |
|
Thiosulfate transmembrane transporter activity GO:0015117
Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other.
|
1 | Q9QZD8 (/ISO) |
|
Malate transmembrane transporter activity GO:0015140
Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
|
1 | O89035 (/IDA) |
|
Malate transmembrane transporter activity GO:0015140
Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
|
1 | Q9QZD8 (/ISO) |
|
Succinate transmembrane transporter activity GO:0015141
Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other.
|
1 | O89035 (/IDA) |
|
Succinate transmembrane transporter activity GO:0015141
Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other.
|
1 | Q9QZD8 (/ISO) |
|
Secondary active transmembrane transporter activity GO:0015291
Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.
|
1 | Q9QZD8 (/IDA) |
|
Antiporter activity GO:0015297
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
|
1 | O89035 (/IDA) |
|
Antiporter activity GO:0015297
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
|
1 | Q9QZD8 (/ISO) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
2 | Q9UBX3 (/TAS) Q9UBX3 (/TAS) |
|
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9UBX3 (/TAS) Q9UBX3 (/TAS) |
|
Dicarboxylic acid transport GO:0006835
The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9UBX3 (/TAS) Q9UBX3 (/TAS) |
|
Sulfide oxidation, using sulfide:quinone oxidoreductase GO:0070221
A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.
|
2 | Q9UBX3 (/TAS) Q9UBX3 (/TAS) |
|
Phosphate ion transport GO:0006817
The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O89035 (/IDA) |
|
Phosphate ion transport GO:0006817
The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9QZD8 (/ISO) |
|
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
|
1 | Q9QZD8 (/ISO) |
|
Sulfate transport GO:0008272
The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O89035 (/IDA) |
|
Sulfate transport GO:0008272
The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9QZD8 (/ISO) |
|
Thiosulfate transport GO:0015709
The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O89035 (/IDA) |
|
Thiosulfate transport GO:0015709
The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9QZD8 (/ISO) |
|
Malate transport GO:0015743
The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O89035 (/IDA) |
|
Malate transport GO:0015743
The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9QZD8 (/ISO) |
|
Succinate transport GO:0015744
The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O89035 (/IDA) |
|
Succinate transport GO:0015744
The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9QZD8 (/ISO) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
7 | A0A0S2Z382 (/IDA) A0A0S2Z382 (/IDA) A0A0S2Z3G3 (/IDA) B4DLN1 (/IDA) Q9QZD8 (/IDA) Q9UBX3 (/IDA) Q9UBX3 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | A0A0S2Z382 (/IDA) A0A0S2Z382 (/IDA) A0A0S2Z3G3 (/IDA) B4DLN1 (/IDA) Q9UBX3 (/IDA) Q9UBX3 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q9UBX3 (/HDA) Q9UBX3 (/HDA) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
2 | Q9UBX3 (/TAS) Q9UBX3 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9QZD8 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9QZD8 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9QZD8 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | O89035 (/TAS) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q9QZD8 (/HDA) |