The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Eukaryotic translation initiation factor 3 subunit...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation regulator activity GO:0045182
Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
1 P34339 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Formation of cytoplasmic translation initiation complex GO:0001732
Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.
1 O74760 (/IC)
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
1 P34339 (/IMP)
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
1 P34339 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O74760 (/HDA)
Eukaryotic translation initiation factor 3 complex GO:0005852
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
1 O74760 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
1 O74760 (/IDA)
Eukaryotic 43S preinitiation complex GO:0016282
A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
1 O74760 (/IDA)
Eukaryotic translation initiation factor 3 complex, eIF3e GO:0071540
An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.
1 O74760 (/IDA)
Eukaryotic translation initiation factor 3 complex, eIF3m GO:0071541
An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m.
1 O74760 (/IDA)