The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Tetratricopeptide repeat domain
".
FunFam 60: Golgi to ER traffic protein 4 homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | F1LXF5 (/IPI) Q7L5D6 (/IPI) |
|
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
1 | Q7L5D6 (/IPI) |
|
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
|
1 | Q9D1H7 (/ISO) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Tail-anchored membrane protein insertion into ER membrane GO:0071816
A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.
|
13 |
A0MT11 (/ISS)
A0MT11 (/ISS)
A1Z3X3 (/ISS)
A4GWN3 (/ISS)
A4QNE0 (/ISS)
B5KFI0 (/ISS)
B5KFI0 (/ISS)
Q0P5I8 (/ISS)
Q5ZKG8 (/ISS)
Q6GLK9 (/ISS)
(3 more) |
|
Cytoplasmic sequestering of protein GO:0051220
The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell.
|
1 | Q7L5D6 (/IMP) |
|
Cytoplasmic sequestering of protein GO:0051220
The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell.
|
1 | Q9D1H7 (/ISO) |
|
Tail-anchored membrane protein insertion into ER membrane GO:0071816
A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.
|
1 | Q7L5D6 (/IDA) |
|
Tail-anchored membrane protein insertion into ER membrane GO:0071816
A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.
|
1 | Q7L5D6 (/IMP) |
|
Tail-anchored membrane protein insertion into ER membrane GO:0071816
A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.
|
1 | Q9D1H7 (/ISO) |
|
Maintenance of unfolded protein involved in ERAD pathway GO:1904378
Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome.
|
1 | Q7L5D6 (/IMP) |
|
Maintenance of unfolded protein involved in ERAD pathway GO:1904378
Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome.
|
1 | Q9D1H7 (/ISO) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
13 |
A0MT11 (/ISS)
A0MT11 (/ISS)
A1Z3X3 (/ISS)
A4GWN3 (/ISS)
A4QNE0 (/ISS)
B5KFI0 (/ISS)
B5KFI0 (/ISS)
Q0P5I8 (/ISS)
Q5ZKG8 (/ISS)
Q6GLK9 (/ISS)
(3 more) |
|
BAT3 complex GO:0071818
A protein complex consisting of BAT3 (BAG6) and its cofactors. In mammals these cofactors are TRC35 (GET4) and UBL4A. It facilitates tail-anchored protein capture by ASNA1/TRC4 and also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD).
|
13 |
A0MT11 (/ISS)
A0MT11 (/ISS)
A1Z3X3 (/ISS)
A4GWN3 (/ISS)
A4QNE0 (/ISS)
B5KFI0 (/ISS)
B5KFI0 (/ISS)
Q0P5I8 (/ISS)
Q5ZKG8 (/ISS)
Q6GLK9 (/ISS)
(3 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q7L5D6 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9D1H7 (/ISO) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q7L5D6 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9D1H7 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q7L5D6 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9D1H7 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q7L5D6 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9D1H7 (/ISO) |
|
BAT3 complex GO:0071818
A protein complex consisting of BAT3 (BAG6) and its cofactors. In mammals these cofactors are TRC35 (GET4) and UBL4A. It facilitates tail-anchored protein capture by ASNA1/TRC4 and also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD).
|
1 | Q7L5D6 (/IDA) |
|
BAT3 complex GO:0071818
A protein complex consisting of BAT3 (BAG6) and its cofactors. In mammals these cofactors are TRC35 (GET4) and UBL4A. It facilitates tail-anchored protein capture by ASNA1/TRC4 and also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD).
|
1 | Q9D1H7 (/ISO) |
