The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 292: Deoxyhypusine hydroxylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P47120 (/IPI) P47120 (/IPI) P47120 (/IPI) P47120 (/IPI) P47120 (/IPI) P47120 (/IPI) P47120 (/IPI) P47120 (/IPI) P47120 (/IPI)
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
9 P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA)
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
9 P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP)
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
5 Q2QLW3 (/ISS) Q2QLW3 (/ISS) Q2QXB3 (/ISS) Q94JW0 (/ISS) Q94JW0 (/ISS)
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
1 Q9P6K9 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
9 P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP)
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
9 P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA) P47120 (/IDA)
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
9 P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP) P47120 (/IMP)
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
5 Q2QLW3 (/ISS) Q2QLW3 (/ISS) Q2QXB3 (/ISS) Q94JW0 (/ISS) Q94JW0 (/ISS)
Filamentous growth of a population of unicellular organisms in response to neutral pH GO:0036178
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.
2 Q59Z14 (/IMP) Q59Z14 (/IMP)
Single-species biofilm formation on inanimate substrate GO:0044011
A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
2 Q59Z14 (/IMP) Q59Z14 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
2 Q59Z14 (/IMP) Q59Z14 (/IMP)
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
1 Q9P6K9 (/ISO)
Regulation of cytoplasmic translation GO:2000765
Any process that modulates the frequency, rate or extent of cytoplasmic translation.
1 Q9P6K9 (/IC)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) Q9P6K9 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA) P47120 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q94JW0 (/IDA) Q94JW0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9P6K9 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9P6K9 (/HDA)