The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Leucine-rich Repeat Variant
".
FunFam 282: Spindle pole body component
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Microtubule plus-end binding GO:0051010
Interacting selectively and non-covalently with the plus end of a microtubule.
|
2 | Q5B1Q9 (/IDA) Q5B1Q9 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O94534 (/IPI) |
|
Microtubule plus-end binding GO:0051010
Interacting selectively and non-covalently with the plus end of a microtubule.
|
1 | O94534 (/TAS) |
|
Microtubule plus end polymerase GO:0061863
Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers.
|
1 | O94534 (/IDA) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of microtubule polymerization or depolymerization GO:0031110
Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.
|
2 | Q5B1Q9 (/IMP) Q5B1Q9 (/IMP) |
|
Microtubule polymerization GO:0046785
The addition of tubulin heterodimers to one or both ends of a microtubule.
|
2 | Q5B1Q9 (/IDA) Q5B1Q9 (/IDA) |
|
Cytoplasmic microtubule organization GO:0031122
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
|
1 | O94534 (/EXP) |
|
Attachment of mitotic spindle microtubules to kinetochore GO:0051315
The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
|
1 | O94534 (/EXP) |
|
Establishment or maintenance of cell polarity regulating cell shape GO:0071963
Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.
|
1 | O94534 (/IMP) |
|
Mitotic spindle assembly GO:0090307
The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.
|
1 | O94534 (/IMP) |
|
Protein transport along microtubule to kinetochore GO:0140210
Any process in which a protein is transported to the kinetochore along a microtubule.
|
1 | O94534 (/IMP) |
There are 14 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasmic microtubule GO:0005881
Any microtubule in the cytoplasm of a cell.
|
3 | O94534 (/IDA) Q5B1Q9 (/IDA) Q5B1Q9 (/IDA) |
|
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
|
2 | Q5B1Q9 (/IDA) Q5B1Q9 (/IDA) |
|
Spindle microtubule GO:0005876
Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
|
2 | Q5B1Q9 (/IDA) Q5B1Q9 (/IDA) |
|
Condensed nuclear chromosome outer kinetochore GO:0000942
The region of a condensed nuclear chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
|
1 | O94534 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O94534 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O94534 (/HDA) |
|
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
|
1 | O94534 (/HDA) |
|
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | O94534 (/HDA) |
|
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | O94534 (/IDA) |
|
TACC/TOG complex GO:0070850
A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.
|
1 | O94534 (/IDA) |
|
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
|
1 | O94534 (/IDA) |
|
Static microtubule bundle GO:0099070
A microtubule bundle that has a constant length, and in which microtubule sliding does not take place.
|
1 | O94534 (/IDA) |
|
Cytoplasmic microtubule plus-end GO:1904511
Any microtubule plus-end that is part of a cytoplasmic microtubule.
|
1 | O94534 (/IDA) |
|
Mitotic spindle microtubule GO:1990498
Any microtubule that is part of a mitotic spindle; anchored at one spindle pole.
|
1 | O94534 (/IDA) |