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CATH Superfamily 1.20.210.10

Cytochrome c oxidase-like, subunit I domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome c oxidase-like, subunit I domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Cytochrome o ubiquinol oxidase, subunit I

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Ubiquinol oxidase (H(+)-transporting). [EC: 7.1.1.3]
2 ubiquinol + O(2) + n H(+)(Side 1) = 2 ubiquinone + 2 H(2)O + n H(+)(Side 2).
  • This terminal oxidase enzyme generates proton motive force by two mechanisms: (1) transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water, and (2) active pumping of protons across the membrane.
  • The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) depends on the enzyme; for example, for the bo(3) oxidase it is 2, while for the bd-II oxidase it is 1.
  • Cf. EC 7.1.1.7.
  • Formerly EC 1.10.3.10.
 22954 A0A023YT60 A0A023YT60 A0A023YT60 A0A023YT60 A0A023YT60 A0A023YT60 A0A023YT60 A0A023YT60 A0A023YT60 A0A023YT60
(22944 more...)
Cytochrome-c oxidase. [EC: 1.9.3.1]
4 ferrocytochrome c + O(2) + 4 H(+) = 4 ferricytochrome c + 2 H(2)O.
  • The reduction of O(2) to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
  • Several bacteria appear to contain analogous oxidases.
 4 A0A2A6NAV5 A0A2A6NAV5 P98057 P98057