CATH Superfamily 1.20.1270.60

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Rho GTPase-activating protein 26	702		-	-	97.7
2	Formin-binding protein 1-like isoform 1	596	3D	2efkA01	-	95.4
3	arfaptin-2 isoform X1	584	3D	4dcnD00	-	84.3
4	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1	545		-	-	73.7
5	Sphingolipid long chain base-responsive pil1	493	3D	3pltC00	-	91.8
6	SLIT-ROBO Rho GTPase-activating protein 1 isoform 2	488		-	-	92.6
7	Bridging integrator 1, isoform CRA_e	455	3D	2ficB00	-	76.2
8	Sorting nexin	453		-	-	94.3
9	Protein kinase C and casein kinase substrate in neurons 2	444	3D	3lllB01	-	94.3
10	Metastasis suppressor 1, isoform CRA_e	399	3D	2d1lB00	-	64.8
11	Brain-specific angiogenesis inhibitor 1-associated protein 2	390	3D	2yktA00	-	87.7
12	Sorting nexin 2	381	3D	4fzsB00	-	92.6
13	Amphiphysin isoform 2	369	3D	4atmA00	-	94.7
14	Protein hob3, variant	347		-	-	90.6
16	FCH domain only protein 2	312	3D	2v0oC00	-	93.9
15	Islet cell autoantigen 1, 69kDa	310		-	-	75.4
17	endophilin-B2 isoform X1	276		-	-	71.4
18	Rho GTPase activating protein 44	254		-	-	82.2
21	Endophilin-A2 isoform 1	237	3D	1zwwB00	-	81.9
19	rho GTPase-activating protein 17 isoform X1	236		-	-	79.0
20	SLIT-ROBO Rho GTPase activating protein 3	230		-	-	56.9
22	Sorting nexin 3 protein	228		-	-	97.5
23	Interacting with PRKCA	222		-	-	86.0
24	growth arrest-specific protein 7 isoform X2	220		-	-	62.9
25	arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2	215		-	-	96.5
26	FCH and double SH3 domains protein 2	206		-	-	78.4
27	dynamin-binding protein isoform X1	185		-	-	67.6
28	Bridging integrator 3 homolog	152		-	-	91.6
29	Tyrosine-protein kinase	140		-	-	90.5
31	Putative DCC-interacting protein 13-beta isoform 2	137	3D	5c5bD01	-	82.6
32	Sorting nexin	135	3D	3dytA02	-	37.9
30	Tyrosine-protein kinase	133	3D	4dylA01	-	84.5
34	DCC-interacting protein 13-alpha isoform X2	130	3D	5c5bC01	-	85.1
33	Sorting nexin	128	3D	4akvB02	-	88.2
35	Sorting nexin 4	111		-	-	38.1
36	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3	106		-	-	94.3
37	Proline-serine-threonine phosphatase interacting protein 1	103		-	-	91.9
38	Rho GTPase activating protein 29	102		-	-	38.0
39	FCH and double SH3 domains protein	99		-	-	82.0
40	GEM-interacting protein isoform X1	99	3D	3qweA00	-	41.7
41	F-BAR and double SH3 domains protein 1	97		-	-	78.5
42	Vacuolar targeting protein Atg24	95		-	-	94.8
43	Brain-specific angiogenesis inhibitor 1-associated protein 2-like 1	94		-	-	91.4
44	Sorting nexin 1	84		-	-	71.8
46	Vacuolar protein sorting-associated protein 17	81		-	-	88.3
45	Cell division control protein	81		-	-	92.5
47	protein FAM92A isoform X1	75		-	-	66.5
48	BAR adaptor protein RVS167	74		-	-	91.7
49	Sorting nexin 8	72		-	-	47.1
50	RhoGAP and Fes/CIP4 domain protein	69		-	-	71.8
51	ARF GTPase activator Csx2	69		-	-	86.2
52	Rho GTPase activating protein 4	69		-	-	63.9
53	SH3 domain-binding protein 1	68		-	-	93.9
54	Proline-serine-threonine phosphatase interacting protein 2	67		-	-	75.7
55	Uncharacterized protein, isoform F	66		-	-	18.8
56	brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2	66	3D	3ok8B00	-	70.2
58	Rho GTPase activating protein 45	58		-	-	25.3
57	Rho guanine nucleotide exchange factor 37	58		-	-	79.6
59	Rho GTPase activating protein 4b	58		-	-	81.6
60	Actin polymerization protein Bzz1	55		-	-	98.8
61	Rho guanine nucleotide exchange factor 38	52		-	-	83.2
62	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1	49	3D	4nswB01	-	61.0
63	Rho GTPase activator	45	3D	4wpcB00	-	95.7
64	Tyrosine-protein kinase	38		-	-	39.0
65	Uncharacterized protein, isoform B	38		-	-	25.1
66	Metastasis suppressor protein 1	38		-	-	25.5
68	Islet cell autoantigen	37		-	-	84.5
67	NOSTRIN isoform 1	37		-	-	33.6
69	Nostrin, isoform D	36		-	-	29.2
70	Uncharacterized protein, isoform C	33		-	-	38.4
71	Uncharacterized protein, isoform U	32		-	-	66.4
72	Sorting nexin MVP1	30		-	-	80.4
74	Rho GTPase-activating protein 42	27		-	-	84.0
73	RhoGAP and Fes/CIP4 domain protein	27		-	-	57.9
75	Related to IVY1-phospholipid-binding protein	26		-	-	86.1
76	Rho GTPase activating protein 42	25		-	-	31.6
78	Slm1p	24		-	-	84.3
77	SH3 domain-containing protein 1	24		-	-	50.6
79	Transcription factor SipA3	24		-	-	71.8
80	ADP-ribosylation factor GTPase-activating protein AGD3	23		-	-	39.3
81	Sorting nexin 2B	23		-	-	60.2
205	Protein kinase C and casein kinase substrate in neurons protein 1	23	3D	3qniB01	-	42.1
82	Endophilin B, isoform C	21		-	-	16.8
84	BAI1-associated protein 2-like 2b	20		-	-	47.4
83	Rho guanyl nucleotide exchange factor, putative	20		-	-	77.6
85	Predicted protein	19		-	-	97.1
86	Rho GTPase-activating protein 10	18		-	-	65.2
87	Rho guanyl nucleotide exchange factor	17		-	-	19.3
89	BAI1 associated protein 2	15		-	-	31.7
91	Sorting nexin 1	15		-	-	74.4
90	Snx4p	15		-	-	29.7
88	Ivy1p	15		-	-	39.3
92	Gvp36p	14		-	-	11.5
93	Rho GTPase-activating protein 92B	14		-	-	18.4
94	SLIT-ROBO Rho GTPase-activating 2 protein	14		-	-	95.3
96	Unplaced genomic scaffold supercont2.2, whole genome shotgun sequence	13		-	-	71.5
95	Hydroxyproline-rich glycoprotein family protein	13		-	-	43.7
97	Vacuolar protein sorting-associated protein 17	13		-	-	43.2
99	Rho guanine nucleotide exchange factor 37	12		-	-	87.4
102	WGS project CABT00000000 data, contig 2.23	12		-	-	91.9
100	Unplaced genomic scaffold supercont2.8, whole genome shotgun sequence	12		-	-	40.8
101	F-BAR and double SH3 domains protein 2 isoform X6	12		-	-	86.6
98	FCH and double SH3 domains protein 2 isoform X3	12		-	-	23.2
105	Ysp1p	11		-	-	9.4
103	Hof1p	11		-	-	17.2
106	Atg20p	11		-	-	12.9
107	Slit-Robo GAP homolog	11		-	-	41.5
104	Unplaced genomic scaffold supercont1.20, whole genome shotgun sequence	11		-	-	9.3
112	YKR078W-like protein	10		-	-	3.1
111	YPR148C-like protein	10		-	-	11.9
113	Atg20p	10		-	-	3.1
110	Sorting nexin	10		-	-	10.7
116	Suppressor of yeast profilin deletion	10	3D	3g9gA00	-	0.8
108	Rho-GTPase-activating protein RGD2	10		-	-	41.6
109	Rho-GTPase-activating protein RGD2	10		-	-	10.4
114	Formin-binding protein 1-like	10		-	-	37.8
119	Unplaced genomic scaffold supercont1.126, whole genome shotgun sequence	9		-	-	7.9
118	Unplaced genomic scaffold supercont1.83, whole genome shotgun sequence	9		-	-	12.5
117	SynDaPiN Synaptic dynamin binding protein	9		-	-	29.8
120	YPR115W-like protein	9		-	-	2.0
121	GTPase activating protein, putative	9		-	-	79.7
115	Putative Dynamin-binding protein	9		-	-	10.4
124	Endophilin-A homolog	8		-	-	11.7
125	Putative phosphoinositide-binding protein	8		-	-	10.8
126	SIP3p Transcription cofactor	8		-	-	0.0
122	Protein CBG22463	8		-	-	21.1
123	Related to SYP1/YCR030C	8		-	-	22.0
128	FCH domain Only FCH stands for Fes/CIP4 homology domain	7		-	-	25.6
132	Rho GTPase Activating protein	7		-	-	0.0
129	Islet cell autoantigen	7		-	-	2.1
131	Variant sh3 domain containing protein	7		-	-	3.0
133	SLIT-ROBO Rho GTPase-activating protein 2	7		-	-	36.0
134	Glucosamine 6-phosphate N-acetyltransferase, putative	7		-	-	79.1
127	Protein CBG03954	7		-	-	26.8
167	Bridging integrator 2	7	3D	4i1qB00	-	35.3
130	Variant sh3 domain containing protein	7		-	-	4.3
142	Rho GTPase-activating protein 92B	6		-	-	7.4
139	Uncharacterized protein	6		-	-	5.4
141	WGS project CABT00000000 data, contig 2.6	6		-	-	7.8
143	Proline-serine-threonine phosphatase-interacting protein 1b	6		-	-	35.7
136	Uncharacterized protein	6		-	-	13.3
137	Uncharacterized protein	6		-	-	14.7
135	GTPase activating protein, putative	6		-	-	11.5
138	Chromosome 9, whole genome shotgun sequence	6		-	-	16.2
140	Variant sh3 domain containing protein	6		-	-	0.5
149	GH04442p	5		-	-	11.1
148	Unplaced genomic scaffold supercont1.21, whole genome shotgun sequence	5		-	-	11.0
144	Uncharacterized protein	5		-	-	68.5
156	SLIT-ROBO Rho GTPase-activating protein 2 isoform X8	5		-	-	30.1
153	Uncharacterized protein	5		-	-	14.8
155	Uncharacterized protein	5		-	-	13.8
154	Sorting nexin-2	5		-	-	3.1
147	Protein CBG09025	5		-	-	11.1
145	Uncharacterized protein	5		-	-	0.0
152	Formin 2,3 and collagen domain containing protein	5		-	-	3.3
146	Glucosamine 6-phosphate N-acetyltransferase	5		-	-	5.7
151	Uncharacterized protein	5		-	-	0.4
150	Arp2/3 complex-activating protein ricka, putative	5		-	-	0.6
158	Bridging integrator 2	4		-	-	12.8
165	BAI1-associated protein 2	4		-	-	62.2
168	Sorting nexin 7	4		-	-	7.7
157	Uncharacterized protein	4		-	-	12.5
163	AGAP009727-PA	4		-	-	13.9
166	Sorting NeXin	4		-	-	65.8
161	Hypothetical_protein_-_conserved	4		-	-	7.0
164	Putative Sip3 protein	4		-	-	0.5
160	ADP-ribosylation factor-interacting protein 2a	4		-	-	47.9
159	Zgc:158689	4		-	-	19.5
162	Rho GTPase-activating protein 17	4		-	-	76.6
170	Rgd3p	3		-	-	1.6
184	Uncharacterized protein	3		-	-	12.3
181	Vacuolar protein sorting-associated protein 17	3		-	-	5.0
178	Cell division control protein, putative	3		-	-	1.3
183	Sorting nexin, putative	3		-	-	9.9
179	sorting nexin-6	3		-	-	0.0
177	Uncharacterized protein	3		-	-	7.5
186	Transcription modulator, putative	3		-	-	6.1
171	Rho GTPase-activating protein 10	3		-	-	4.4
176	Uncharacterized protein	3		-	-	2.5
185	Uncharacterized protein	3		-	-	12.3
180	Vacuolar protein sorting-associated protein 17	3		-	-	0.0
175	SH3 domain signalling protein AFU_orthologue AFUA_5G07670	3		-	-	8.1
174	Meiotically up-regulated gene 137 protein	3		-	-	79.5
182	Autophagy-related protein 24	3		-	-	0.0
173	Uncharacterized protein	3		-	-	9.8
169	Rgd3p	3		-	-	4.4
172	Protein kinase C and casein kinase substrate in neurons 3	3		-	-	30.3
191	Uncharacterized protein	2		-	-	0.0
232	Uncharacterized protein	2		-	-	0.5
225	YALI0F19778p	2		-	-	0.0
207	YALI0F01694p	2		-	-	0.0
222	Uncharacterized protein	2		-	-	17.1
217	Uncharacterized protein	2		-	-	0.4
209	Bridging integrator 3-like protein	2		-	-	0.0
224	Uncharacterized protein	2		-	-	0.0
192	YALI0D07524p	2		-	-	0.0
233	Uncharacterized protein	2		-	-	16.6
199	Uncharacterized protein	2		-	-	0.0
204	Uncharacterized protein	2		-	-	13.3
236	Rho GTPase-activating protein gacP	2		-	-	15.6
234	YALI0E13904p	2		-	-	0.0
193	YALI0F13673p	2		-	-	0.0
227	Uncharacterized protein	2		-	-	0.0
214	GRAF	2		-	-	6.9
196	AaceriAFR725Cp	2		-	-	4.3
194	Dynamin-binding protein	2		-	-	0.0
226	Brain-specific angiogenesis inhibitor 1-associated protein 2	2		-	-	2.6
244	Rho-GTPase-activating protein 8	2		-	-	38.6
237	Mental retardation GTPase activating protein homolog 4	2		-	-	20.0
235	Uncharacterized protein	2		-	-	6.6
215	Uncharacterized protein	2		-	-	0.0
246	Uncharacterized protein	2		-	-	39.6
187	YALI0E05489p	2		-	-	2.4
212	Uncharacterized protein	2		-	-	0.0
198	YALI0B15686p	2		-	-	0.0
202	Uncharacterized protein	2		-	-	1.5
229	Sdpn-1	2		-	-	0.0
247	Rho GTPase-activating protein 4	2		-	-	21.0
210	arfaptin-2-like isoform X2	2		-	-	1.0
242	Uncharacterized protein	2		-	-	0.0
213	Chromosome 13 SCAF14555, whole genome shotgun sequence	2		-	-	8.9
200	Uncharacterized protein	2		-	-	0.0
195	Age1p	2		-	-	0.6
188	Uncharacterized protein	2		-	-	20.9
243	Islet cell autoantigen, putative	2		-	-	37.6
203	rho GTPase-activating protein 26	2		-	-	0.0
228	Protein kinase C and casein kinase substrate in neurons protein 1	2		-	-	0.4
238	Uncharacterized protein	2		-	-	39.8
211	Bridging integrator 1b	2		-	-	6.3
218	AEL147Wp	2		-	-	6.8
189	Dip13 beta, putative	2		-	-	45.4
221	SH3 domain-containing protein	2		-	-	12.6
240	rho GTPase-activating protein 17 isoform X1	2		-	-	0.0
230	AaceriABR082Wp	2		-	-	4.6
239	Uncharacterized protein	2		-	-	2.0
219	Uncharacterized protein	2		-	-	9.9
206	Uncharacterized protein	2		-	-	5.5
220	SH3 and F-BAR domain-containing protein DDB_G0274695	2		-	-	19.3
197	YALI0B15686p	2		-	-	0.0
245	Uncharacterized protein	2		-	-	45.9
208	YALI0C03245p	2		-	-	0.0
241	Nitric oxide synthase-trafficking	2		-	-	0.5
201	growth arrest-specific protein 7	2		-	-	0.0
190	Uncharacterized protein	2		-	-	39.3
231	Uncharacterized protein	2		-	-	0.0
223	F-BAR and double SH3 domains protein 2	2		-	-	0.4
216	Fcho-1	2		-	-	3.0
311	Uncharacterized protein	1		-	-	0.0
272	Protein kinase C alpha binding protein, putative	1		-	-	0.0
294	Asap2a protein	1		-	-	0.0
262	Predicted protein	1		-	-	0.0
278	Uncharacterized protein	1		-	-	0.0
326	SH3-domain GRB2-like 3b	1		-	-	0.0
335	Uncharacterized protein	1		-	-	0.0
305	Uncharacterized protein	1		-	-	0.0
281	Uncharacterized protein	1		-	-	0.0
319	Bridging integrator, putative	1		-	-	0.0
336	Uncharacterized protein	1		-	-	0.0
252	Uncharacterized protein	1		-	-	0.0
329	Sorting nexin-41	1		-	-	0.0
279	Uncharacterized protein	1		-	-	0.0
263	Rho GTPase-activating protein 26-like Protein	1		-	-	0.0
293	Uncharacterized protein	1		-	-	0.0
310	Uncharacterized protein	1		-	-	0.0
267	LD28528p	1		-	-	0.0
280	Uncharacterized protein	1		-	-	0.0
273	Zgc:158689	1		-	-	0.0
334	Rho GTPase-activating protein 44	1		-	-	0.0
253	Chromosome 19, whole genome shotgun sequence	1		-	-	0.0
258	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	1		-	-	0.0
318	Uncharacterized protein	1		-	-	0.0
248	Chromosome 16, whole genome shotgun sequence	1		-	-	0.0
337	Uncharacterized protein	1		-	-	0.0
288	FES proto-oncogene, tyrosine kinase	1		-	-	0.0
260	Uncharacterized protein	1		-	-	0.0
264	Uncharacterized protein	1		-	-	0.0
259	Uncharacterized protein	1		-	-	0.0
320	AGAP001369-PA	1		-	-	0.0
249	Probable Rho-GTPase-activating protein 9	1		-	-	0.0
338	Uncharacterized protein	1		-	-	0.0
328	Uncharacterized protein	1		-	-	0.0
297	Uncharacterized protein	1		-	-	0.0
283	Uncharacterized protein	1		-	-	0.0
295	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	1		-	-	0.0
300	Uncharacterized protein	1		-	-	0.0
296	Uncharacterized protein	1		-	-	0.0
265	Uncharacterized protein	1		-	-	0.0
256	Rho-GTPase-activating protein 8	1		-	-	0.0
270	Uncharacterized protein	1		-	-	0.0
343	Uncharacterized protein	1		-	-	0.0
261	Predicted protein	1		-	-	0.0
321	Ubp4-interactor sfp47	1		-	-	0.0
282	Uncharacterized protein	1		-	-	0.0
306	Meiotically up-regulated gene 64 protein	1		-	-	0.0
340	Uncharacterized PH domain-containing protein C19A8.02	1		-	-	0.0
285	Uncharacterized protein	1		-	-	0.0
308	Uncharacterized protein	1		-	-	0.0
301	Uncharacterized protein	1		-	-	0.0
323	Insulin receptor tyrosine kinase substrate, putative	1		-	-	0.0
330	Uncharacterized protein	1		-	-	0.0
257	BAR domaincontaining protein	1		-	-	0.0
307	Uncharacterized protein	1		-	-	0.0
299	Uncharacterized protein	1		-	-	0.0
315	Uncharacterized protein	1		-	-	0.0
317	Variant SH3 domain containing protein	1		-	-	0.0
284	Predicted protein	1		-	-	0.0
289	Uncharacterized protein	1		-	-	0.0
290	Protein kinase C and casein kinase substrate in neurons 1a	1		-	-	0.0
271	Uncharacterized protein	1		-	-	0.0
342	Uncharacterized protein	1		-	-	0.0
341	Uncharacterized protein	1		-	-	0.0
309	Uncharacterized protein	1		-	-	0.0
254	Inositol-pentakisphosphate 2-kinase	1		-	-	0.0
322	Uncharacterized protein	1		-	-	0.0
316	DDEFL1 protein	1		-	-	0.0
314	Uncharacterized protein	1		-	-	0.0
302	Uncharacterized protein	1		-	-	0.0
298	Uncharacterized protein	1		-	-	0.0
339	AFR651Wp	1		-	-	0.0
268	Zgc:158689	1		-	-	0.0
325	Predicted protein	1		-	-	0.0
287	Uncharacterized protein	1		-	-	0.0
333	Uncharacterized protein	1		-	-	0.0
255	Uncharacterized protein	1		-	-	0.0
274	Uncharacterized protein	1		-	-	0.0
303	Uncharacterized protein	1		-	-	0.0
250	Uncharacterized protein	1		-	-	0.0
276	Dip13 beta, putative	1		-	-	0.0
269	Uncharacterized protein	1		-	-	0.0
313	BAI1-associated protein 2b	1		-	-	0.0
331	Uncharacterized protein	1		-	-	0.0
324	Uncharacterized protein	1		-	-	0.0
312	Uncharacterized protein	1		-	-	0.0
286	Uncharacterized protein	1		-	-	0.0
275	Uncharacterized protein	1		-	-	0.0
251	Chromosome 1, whole genome shotgun sequence	1		-	-	0.0
332	Predicted protein	1		-	-	0.0
292	Bridging integrator 2b	1		-	-	0.0
291	Predicted protein	1		-	-	0.0
327	Uncharacterized protein	1		-	-	0.0
266	Uncharacterized protein	1		-	-	0.0
277	Uncharacterized protein	1		-	-	0.0
304	Uncharacterized protein	1		-	-	0.0