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CATH Superfamily 1.20.1260.10

Ferritin, core subunit, four-helix bundle

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Non-heme ferritin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ferroxidase activity GO:0004322
Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.
 158 P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA)
(148 more)
Ferric iron binding GO:0008199
Interacting selectively and non-covalently with ferric iron, Fe(III).
 158 P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA)
(148 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 158 P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA)
(148 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 64 B6DMH6 (/IPI) O29424 (/IPI) Q9ZLI1 (/IPI) Q9ZLI1 (/IPI) Q9ZLI1 (/IPI) Q9ZLI1 (/IPI) Q9ZLI1 (/IPI) Q9ZLI1 (/IPI) Q9ZLI1 (/IPI) Q9ZLI1 (/IPI)
(54 more)
Ferric iron binding GO:0008199
Interacting selectively and non-covalently with ferric iron, Fe(III).
 6 Q9KVR1 (/ISS) Q9KVR1 (/ISS) Q9KVR1 (/ISS) Q9KVR1 (/ISS) Q9KVR1 (/ISS) Q9KVR1 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
 187 B5Z726 (/IDA) B5Z726 (/IDA) B5Z726 (/IDA) B5Z726 (/IDA) B5Z726 (/IDA) B5Z726 (/IDA) B5Z726 (/IDA) B5Z726 (/IDA) B5Z726 (/IDA) B5Z726 (/IDA)
(177 more)
Intracellular sequestering of iron ion GO:0006880
The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system.
 158 P0A998 (/IMP) P0A998 (/IMP) P0A998 (/IMP) P0A998 (/IMP) P0A998 (/IMP) P0A998 (/IMP) P0A998 (/IMP) P0A998 (/IMP) P0A998 (/IMP) P0A998 (/IMP)
(148 more)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
 158 P0A998 (/IEP) P0A998 (/IEP) P0A998 (/IEP) P0A998 (/IEP) P0A998 (/IEP) P0A998 (/IEP) P0A998 (/IEP) P0A998 (/IEP) P0A998 (/IEP) P0A998 (/IEP)
(148 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
 158 P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA)
(148 more)
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
 29 B5Z726 (/IEP) B5Z726 (/IEP) B5Z726 (/IEP) B5Z726 (/IEP) B5Z726 (/IEP) B5Z726 (/IEP) B5Z726 (/IEP) B5Z726 (/IEP) B5Z726 (/IEP) B5Z726 (/IEP)
(19 more)
Intracellular sequestering of iron ion GO:0006880
The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system.
 6 Q9KVR1 (/ISS) Q9KVR1 (/ISS) Q9KVR1 (/ISS) Q9KVR1 (/ISS) Q9KVR1 (/ISS) Q9KVR1 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 158 P0A998 (/HDA) P0A998 (/HDA) P0A998 (/HDA) P0A998 (/HDA) P0A998 (/HDA) P0A998 (/HDA) P0A998 (/HDA) P0A998 (/HDA) P0A998 (/HDA) P0A998 (/HDA)
(148 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 158 P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA) P0A998 (/IDA)
(148 more)