The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Sec23/Sec24 helical domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Protein transport protein Sec24C isoform C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
9 A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q80V21 (/ISO) Q8CGF4 (/ISO) Q8R0M3 (/ISO) Q8R2V9 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
9 A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q80V21 (/ISO) Q8CGF4 (/ISO) Q8R0M3 (/ISO) Q8R2V9 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 O94855 (/IPI) P53992 (/IPI) P53992 (/IPI) Q3V222 (/IPI) Q8R2V9 (/IPI)
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
3 O94855 (/IPI) P53992 (/IPI) P53992 (/IPI)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
3 O94855 (/IDA) P53992 (/IDA) P53992 (/IDA)

There are 31 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
9 A0A286YDI8 (/IMP) G3X972 (/IMP) Q3V222 (/IMP) Q6NXL1 (/IMP) Q80U83 (/IMP) Q80V21 (/IMP) Q8CGF4 (/IMP) Q8R0M3 (/IMP) Q8R2V9 (/IMP)
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
9 A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q80V21 (/ISO) Q8CGF4 (/ISO) Q8R0M3 (/ISO) Q8R2V9 (/ISO)
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
9 A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q80V21 (/ISO) Q8CGF4 (/ISO) Q8R0M3 (/ISO) Q8R2V9 (/ISO)
Antigen processing and presentation of peptide antigen via MHC class I GO:0002474
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
3 O94855 (/TAS) P53992 (/TAS) P53992 (/TAS)
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
3 O94855 (/IMP) P53992 (/IMP) P53992 (/IMP)
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
3 O94855 (/NAS) P53992 (/NAS) P53992 (/NAS)
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
3 O94855 (/TAS) P53992 (/TAS) P53992 (/TAS)
Antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
3 O94855 (/TAS) P53992 (/TAS) P53992 (/TAS)
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
3 O94855 (/TAS) P53992 (/TAS) P53992 (/TAS)
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
3 O94855 (/IDA) P53992 (/IDA) P53992 (/IDA)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Positive regulation of extracellular matrix constituent secretion GO:0003331
Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Protein secretion GO:0009306
The controlled release of proteins from a cell.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Muscle attachment GO:0016203
The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Positive regulation of cell-cell adhesion GO:0022409
Any process that activates or increases the rate or extent of cell adhesion to another cell.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Maintenance of cell polarity GO:0030011
The maintenance of established anisotropic intracellular organization or cell growth patterns.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Protein localization to cell surface GO:0034394
A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Lumen formation, open tracheal system GO:0035149
Creation of the central hole of a tube in an open tracheal system through which gases flow.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Regulation of tube size, open tracheal system GO:0035151
Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Regulation of tube diameter, open tracheal system GO:0035158
Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Chitin-based cuticle development GO:0040003
Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Positive regulation of cuticle pigmentation GO:0048081
Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
2 D5LMH4 (/IMP) F1QRB4 (/IMP)
Cartilage morphogenesis GO:0060536
The process in which the anatomical structures of cartilage are generated and organized.
2 D5LMH4 (/IMP) F1QRB4 (/IMP)
Extracellular matrix constituent secretion GO:0070278
The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.
2 D5LMH4 (/IMP) F1QRB4 (/IMP)
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
2 M9PC99 (/IMP) Q9VQ94 (/IMP)
COPII-coated vesicle cargo loading GO:0090110
The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
2 M9PC99 (/ISS) Q9VQ94 (/ISS)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
9 A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q6NXL1 (/ISO) Q80U83 (/ISO) Q80V21 (/ISO) Q8CGF4 (/ISO) Q8R0M3 (/ISO) Q8R2V9 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
6 A0A286YDI8 (/ISO) G3X972 (/ISO) Q3V222 (/ISO) Q80U83 (/ISO) Q8CGF4 (/ISO) Q8R2V9 (/ISO)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
3 O94855 (/TAS) P53992 (/TAS) P53992 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O94855 (/TAS) P53992 (/TAS) P53992 (/TAS)
ER to Golgi transport vesicle membrane GO:0012507
The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
3 O94855 (/TAS) P53992 (/TAS) P53992 (/TAS)
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
3 O94855 (/IDA) P53992 (/IDA) P53992 (/IDA)
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
3 O94855 (/NAS) P53992 (/NAS) P53992 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P53992 (/IDA) P53992 (/IDA)
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
2 M9PC99 (/ISS) Q9VQ94 (/ISS)
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
2 M9PC99 (/IDA) Q9VQ94 (/IDA)