The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Rhodopsin 7-helix transmembrane proteins
".
FunFam 180: neuropeptide Y receptor type 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Peptide YY receptor activity GO:0001601
Combining with gut peptide YY to initiate a change in cell activity.
|
3 | O70342 (/IDA) O70342 (/IDA) Q63634 (/IDA) |
Pancreatic polypeptide receptor activity GO:0001602
Combining with pancreatic polypeptide PP to initiate a change in cell activity.
|
3 | O70342 (/IDA) O70342 (/IDA) Q63634 (/IDA) |
Neuropeptide Y receptor activity GO:0004983
Combining with neuropeptide Y to initiate a change in cell activity.
|
3 | O70342 (/IDA) O70342 (/IDA) Q63634 (/IDA) |
Neuropeptide Y receptor activity GO:0004983
Combining with neuropeptide Y to initiate a change in cell activity.
|
3 | Q15761 (/TAS) Q15761 (/TAS) Q15761 (/TAS) |
Peptide YY receptor activity GO:0001601
Combining with gut peptide YY to initiate a change in cell activity.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Pancreatic polypeptide receptor activity GO:0001602
Combining with pancreatic polypeptide PP to initiate a change in cell activity.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Neuropeptide Y receptor activity GO:0004983
Combining with neuropeptide Y to initiate a change in cell activity.
|
2 | O70342 (/ISO) O70342 (/ISO) |
There are 27 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
3 | Q15761 (/IMP) Q15761 (/IMP) Q15761 (/IMP) |
Cardiac left ventricle morphogenesis GO:0003214
The process in which the left cardiac ventricle is generated and organized.
|
3 | Q15761 (/IMP) Q15761 (/IMP) Q15761 (/IMP) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
3 | Q15761 (/TAS) Q15761 (/TAS) Q15761 (/TAS) |
Positive regulation of acute inflammatory response GO:0002675
Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Negative regulation of acute inflammatory response to antigenic stimulus GO:0002865
Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Cardiac left ventricle morphogenesis GO:0003214
The process in which the left cardiac ventricle is generated and organized.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
2 | O70342 (/IMP) O70342 (/IMP) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Negative regulation of glutamate secretion GO:0014050
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Negative regulation of synaptic transmission, GABAergic GO:0032229
Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
2 | O70342 (/ISO) O70342 (/ISO) |
Eating behavior GO:0042755
The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Generation of ovulation cycle rhythm GO:0060112
The process which controls the timing of the type of sexual cycle seen in female mammals.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Positive regulation of acute inflammatory response GO:0002675
Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.
|
1 | Q63634 (/IMP) |
Negative regulation of acute inflammatory response to antigenic stimulus GO:0002865
Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
|
1 | Q63634 (/IDA) |
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
1 | Q63634 (/IEP) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q63634 (/IMP) |
Negative regulation of glutamate secretion GO:0014050
Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.
|
1 | Q63634 (/IMP) |
Negative regulation of synaptic transmission, GABAergic GO:0032229
Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
|
1 | Q63634 (/IMP) |
Eating behavior GO:0042755
The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
|
1 | Q63634 (/IMP) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q63634 (/IMP) |
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
1 | Q63634 (/IMP) |
Generation of ovulation cycle rhythm GO:0060112
The process which controls the timing of the type of sexual cycle seen in female mammals.
|
1 | Q63634 (/IMP) |
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q63634 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q15761 (/TAS) Q15761 (/TAS) Q15761 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | Q15761 (/TAS) Q15761 (/TAS) Q15761 (/TAS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | O70342 (/ISO) O70342 (/ISO) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | O70342 (/IDA) O70342 (/IDA) |
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
2 | O70342 (/IDA) O70342 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q63634 (/IDA) |