The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 74: Elongation factor 1-gamma 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
10 P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
10 P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP)
Guanyl-nucleotide exchange factor activity GO:0005085
Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
10 P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
10 P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA)
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
10 P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational elongation GO:0006414
The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
10 P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA)
Regulation of translational termination GO:0006449
Any process that modulates the frequency, rate or extent of translational termination.
10 P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
10 P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI) P29547 (/IGI)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
10 P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP) P29547 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA)
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
10 P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA) P29547 (/IDA)