The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 35: Hematopoietic prostaglandin D synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
4 O35543 (/ISS) O73888 (/ISS) O73888 (/ISS) Q9JHF7 (/ISS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
4 O35543 (/ISS) O73888 (/ISS) O73888 (/ISS) Q9JHF7 (/ISS)
Prostaglandin-D synthase activity GO:0004667
Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
3 O60760 (/IDA) O60760 (/IDA) Q9JHF7 (/IDA)
Prostaglandin-D synthase activity GO:0004667
Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
3 O35543 (/ISS) O73888 (/ISS) O73888 (/ISS)
Prostaglandin-D synthase activity GO:0004667
Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
3 O35543 (/TAS) O60760 (/TAS) O60760 (/TAS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 O60760 (/IDA) O60760 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 O60760 (/IDA) O60760 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O60760 (/IPI) O60760 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 O60760 (/IPI) O60760 (/IPI)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q9JHF7 (/ISO)
Glutathione transferase activity GO:0004364
Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
1 Q9JHF7 (/ISO)
Prostaglandin-D synthase activity GO:0004667
Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
1 Q9JHF7 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q9JHF7 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9JHF7 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Prostaglandin metabolic process GO:0006693
The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
3 O60760 (/IDA) O60760 (/IDA) Q9JHF7 (/IDA)
Prostaglandin metabolic process GO:0006693
The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
3 O35543 (/ISS) O73888 (/ISS) O73888 (/ISS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
2 O60760 (/NAS) O60760 (/NAS)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
2 O60760 (/TAS) O60760 (/TAS)
Cyclooxygenase pathway GO:0019371
The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.
2 O60760 (/TAS) O60760 (/TAS)
Glutathione derivative biosynthetic process GO:1901687
The chemical reactions and pathways resulting in the formation of glutathione derivative.
2 O60760 (/TAS) O60760 (/TAS)
Prostaglandin biosynthetic process GO:0001516
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
1 O35543 (/TAS)
Prostaglandin metabolic process GO:0006693
The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
1 Q9JHF7 (/ISO)
Negative regulation of male germ cell proliferation GO:2000255
Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.
1 Q9JHF7 (/IGI)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 O60760 (/TAS) O60760 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O60760 (/TAS) O60760 (/TAS)