The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DNA helicase RuvA subunit, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 52: Huntingtin-interacting protein K (Predicted)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
17 Q9CR41 (/IPI) Q9CR41 (/IPI) Q9CR41 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI)
(7 more)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
14 Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI) Q9NX55 (/IPI)
(4 more)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
3 Q9CR41 (/ISO) Q9CR41 (/ISO) Q9CR41 (/ISO)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
14 Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA)
(4 more)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
14 Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA)
(4 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
3 Q9CR41 (/ISO) Q9CR41 (/ISO) Q9CR41 (/ISO)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
3 Q9CR41 (/ISO) Q9CR41 (/ISO) Q9CR41 (/ISO)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
28 A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA)
(18 more)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
28 A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA) A0A024R5Q1 (/IDA)
(18 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
17 Q9CR41 (/IDA) Q9CR41 (/IDA) Q9CR41 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA)
(7 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
14 Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA)
(4 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
14 Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA) Q9NX55 (/IDA)
(4 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q9CR41 (/ISO) Q9CR41 (/ISO) Q9CR41 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q9CR41 (/ISO) Q9CR41 (/ISO) Q9CR41 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q9CR41 (/ISO) Q9CR41 (/ISO) Q9CR41 (/ISO)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
3 Q9CR41 (/ISO) Q9CR41 (/ISO) Q9CR41 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
3 Q9CR41 (/ISO) Q9CR41 (/ISO) Q9CR41 (/ISO)