The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Thymopoietin isoform alpha

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
8 Q5RGX2 (/IDA) Q5RGX4 (/IDA) Q5RGX5 (/IDA) Q7ZTV0 (/IDA) Q8UUR4 (/IDA) Q8UUR5 (/IDA) Q8UUR6 (/IDA) Q8UUR7 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P42166 (/IPI) P42167 (/IPI) P42167 (/IPI) P42167 (/IPI) Q61029 (/IPI) Q61033 (/IPI) Q62733 (/IPI) Q9XTB5 (/IPI)
Lamin binding GO:0005521
Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
5 P42166 (/TAS) P42167 (/TAS) P42167 (/TAS) P42167 (/TAS) Q62733 (/TAS)
Lamin binding GO:0005521
Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
1 Q9XTB5 (/IDA)
Lamin binding GO:0005521
Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
1 O01971 (/IPI)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 Q9XTB5 (/IDA)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
1 P42166 (/HDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitotic nuclear envelope reassembly GO:0007084
The cell cycle process that results in reformation of the nuclear envelope during mitotic cell division.
8 Q5RGX2 (/IDA) Q5RGX4 (/IDA) Q5RGX5 (/IDA) Q7ZTV0 (/IDA) Q8UUR4 (/IDA) Q8UUR5 (/IDA) Q8UUR6 (/IDA) Q8UUR7 (/IDA)
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
2 O01971 (/IGI) Q9XTB5 (/IGI)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 Q61029 (/IDA) Q61033 (/IDA)
Chromosome segregation GO:0007059
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
2 O01971 (/IGI) Q9XTB5 (/IGI)
Response to X-ray GO:0010165
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
2 O01971 (/IMP) Q9XTB5 (/IMP)
Nuclear envelope reassembly GO:0031468
The reformation of the nuclear envelope following its breakdown in the context of a normal process.
1 Q62733 (/NAS)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Condensed chromosome GO:0000793
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
8 Q5RGX2 (/IDA) Q5RGX4 (/IDA) Q5RGX5 (/IDA) Q7ZTV0 (/IDA) Q8UUR4 (/IDA) Q8UUR5 (/IDA) Q8UUR6 (/IDA) Q8UUR7 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
8 Q5RGX2 (/IDA) Q5RGX4 (/IDA) Q5RGX5 (/IDA) Q7ZTV0 (/IDA) Q8UUR4 (/IDA) Q8UUR5 (/IDA) Q8UUR6 (/IDA) Q8UUR7 (/IDA)
Nuclear outer membrane-endoplasmic reticulum membrane network GO:0042175
The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.
8 Q5RGX2 (/IDA) Q5RGX4 (/IDA) Q5RGX5 (/IDA) Q7ZTV0 (/IDA) Q8UUR4 (/IDA) Q8UUR5 (/IDA) Q8UUR6 (/IDA) Q8UUR7 (/IDA)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
7 O01971 (/IDA) P42167 (/IDA) P42167 (/IDA) P42167 (/IDA) Q61029 (/IDA) Q61033 (/IDA) Q9XTB5 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
6 A0A024RBE7 (/IDA) A0A024RBE7 (/IDA) A0A024RBE7 (/IDA) P42167 (/IDA) P42167 (/IDA) P42167 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 P42166 (/TAS) P42167 (/TAS) P42167 (/TAS) P42167 (/TAS)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
4 P42166 (/TAS) P42167 (/TAS) P42167 (/TAS) P42167 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
3 P42167 (/HDA) P42167 (/HDA) P42167 (/HDA)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
2 Q61029 (/ISO) Q61033 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q61029 (/ISO) Q61033 (/ISO)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
2 Q61029 (/ISO) Q61033 (/ISO)
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
2 Q61029 (/ISO) Q61033 (/ISO)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
2 Q61029 (/ISO) Q61033 (/ISO)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
1 P42166 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P42166 (/IDA)
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
1 Q62733 (/IDA)
Integral component of nuclear inner membrane GO:0005639
The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 O01971 (/IDA)