The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Cytochrome P450 26B1 isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Retinoic acid 4-hydroxylase activity GO:0008401
Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
4 E1BHJ4 (/ISS) E1BHJ4 (/ISS) Q08D50 (/ISS) Q6EIG3 (/ISS)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen GO:0016709
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
4 E1BHJ4 (/ISS) E1BHJ4 (/ISS) G3V7X8 (/ISS) Q811W2 (/ISS)
Retinoic acid binding GO:0001972
Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
2 Q6V0L0 (/IDA) Q9NR63 (/IDA)
Retinoic acid binding GO:0001972
Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
2 B2RXA7 (/ISO) Q811W2 (/ISO)
Retinoic acid 4-hydroxylase activity GO:0008401
Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
2 Q6V0L0 (/IDA) Q9NR63 (/IDA)
Retinoic acid 4-hydroxylase activity GO:0008401
Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
2 B2RXA7 (/ISO) Q811W2 (/ISO)
Retinoic acid 4-hydroxylase activity GO:0008401
Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
1 G3V7X8 (/IMP)
Retinoic acid 4-hydroxylase activity GO:0008401
Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
1 Q6V0L0 (/TAS)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen GO:0016709
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
1 Q9NR63 (/IDA)
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen GO:0016709
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
1 Q811W2 (/ISO)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
1 Q9NR63 (/NAS)

There are 63 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
4 E1BHJ4 (/ISS) E1BHJ4 (/ISS) G3V7X8 (/ISS) Q811W2 (/ISS)
Retinoic acid catabolic process GO:0034653
The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.
3 E1BHJ4 (/ISS) E1BHJ4 (/ISS) Q08D50 (/ISS)
Vitamin metabolic process GO:0006766
The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
2 Q6V0L0 (/TAS) Q9NR63 (/TAS)
Retinoic acid catabolic process GO:0034653
The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.
2 Q6V0L0 (/IDA) Q9NR63 (/IDA)
Retinoic acid catabolic process GO:0034653
The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.
2 G3V7X8 (/IMP) Q6EIG3 (/IMP)
Retinoic acid catabolic process GO:0034653
The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.
2 B2RXA7 (/ISO) Q811W2 (/ISO)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 Q6V0L0 (/IDA) Q9NR63 (/IDA)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 B2RXA7 (/ISO) Q811W2 (/ISO)
Bone morphogenesis GO:0060349
The process in which bones are generated and organized.
2 Q6EIG3 (/IMP) Q9NR63 (/IMP)
Bone morphogenesis GO:0060349
The process in which bones are generated and organized.
2 E1BHJ4 (/ISS) E1BHJ4 (/ISS)
Cell fate determination GO:0001709
A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
1 Q811W2 (/IMP)
Cell fate determination GO:0001709
A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
1 Q9NR63 (/ISS)
Establishment of T cell polarity GO:0001768
The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
1 Q811W2 (/IMP)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1 G3V7X8 (/IEP)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 Q9NR63 (/IDA)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 Q811W2 (/ISO)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
1 Q811W2 (/IMP)
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
1 Q811W2 (/IMP)
Male meiotic nuclear division GO:0007140
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
1 Q9NR63 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q811W2 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q9NR63 (/ISS)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
1 B2RXA7 (/IGI)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
1 Q6V0L0 (/ISS)
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
1 B2RXA7 (/IGI)
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
1 Q6V0L0 (/ISS)
Proximal/distal pattern formation GO:0009954
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
1 Q811W2 (/IMP)
Proximal/distal pattern formation GO:0009954
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
1 Q9NR63 (/ISS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q811W2 (/IMP)
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
1 B2RXA7 (/IGI)
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
1 Q6V0L0 (/ISS)
Rhombomere 4 morphogenesis GO:0021661
The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
1 Q6EIG3 (/IGI)
Regulation of ossification GO:0030278
Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
1 Q6EIG3 (/IMP)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
1 Q811W2 (/IMP)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
1 Q9NR63 (/ISS)
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
1 Q6EIG3 (/IGI)
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
1 G3V7X8 (/IEP)
Response to vitamin A GO:0033189
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
1 G3V7X8 (/IEP)
Retinoic acid catabolic process GO:0034653
The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.
1 Q811W2 (/IC)
Tendon formation GO:0035992
The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.
1 Q6EIG3 (/IMP)
Odontogenesis GO:0042476
The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
1 Q6EIG3 (/IMP)
Retinoic acid metabolic process GO:0042573
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
1 Q811W2 (/IC)
Retinoic acid metabolic process GO:0042573
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
1 Q6EIG3 (/TAS)
Tongue morphogenesis GO:0043587
The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
1 Q811W2 (/IMP)
Regulation of T cell differentiation GO:0045580
Any process that modulates the frequency, rate or extent of T cell differentiation.
1 Q811W2 (/IMP)
Organelle fusion GO:0048284
The creation of a single organelle from two or more organelles.
1 B2RXA7 (/IGI)
Organelle fusion GO:0048284
The creation of a single organelle from two or more organelles.
1 Q6V0L0 (/ISS)
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
1 Q811W2 (/IDA)
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
1 Q811W2 (/IMP)
Regulation of retinoic acid receptor signaling pathway GO:0048385
Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
1 Q811W2 (/IMP)
Negative regulation of retinoic acid receptor signaling pathway GO:0048387
Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
1 Q6EIG3 (/IDA)
Negative regulation of retinoic acid receptor signaling pathway GO:0048387
Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
1 Q811W2 (/IMP)
Negative regulation of retinoic acid receptor signaling pathway GO:0048387
Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
1 Q6V0L0 (/NAS)
Negative regulation of retinoic acid receptor signaling pathway GO:0048387
Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
1 Q9NR63 (/TAS)
Embryonic cranial skeleton morphogenesis GO:0048701
The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
1 Q6EIG3 (/IMP)
Head morphogenesis GO:0060323
The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.
1 Q6EIG3 (/IMP)
Bone morphogenesis GO:0060349
The process in which bones are generated and organized.
1 Q811W2 (/ISO)
Cranial suture morphogenesis GO:0060363
The process in which any suture between cranial bones is generated and organized.
1 Q6EIG3 (/IMP)
Coronal suture morphogenesis GO:0060365
The process in which the coronal suture is generated and organized.
1 Q6EIG3 (/IMP)
Cartilage morphogenesis GO:0060536
The process in which the anatomical structures of cartilage are generated and organized.
1 Q6EIG3 (/IMP)
Establishment of skin barrier GO:0061436
Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
1 Q811W2 (/IMP)
Cornification GO:0070268
A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).
1 Q811W2 (/IMP)
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
1 Q811W2 (/IEP)
Positive regulation of tongue muscle cell differentiation GO:2001037
Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.
1 Q811W2 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 Q6V0L0 (/TAS) Q9NR63 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9NR63 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q811W2 (/ISO)