The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 72: 3-hydroxyphenylacetate 6 hydroxylase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phenylacetate 2-hydroxylase. [EC: 1.14.14.54]
Phenylacetate + [reduced NADPH--hemoprotein reductase] + O(2) = (2-hydroxyphenyl)acetate + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • This cytochrome P450 enzyme, found in Aspergillus nidulans, is involved in the degradation of phenylacetate.
9 A0A1U8QNQ0 A0A1U8QNQ0 A0A1U8QNQ0 G5EAX2 G5EAX2 G5EAX2 Q9Y7G5 Q9Y7G5 Q9Y7G5
3-hydroxyphenylacetate 6-hydroxylase. [EC: 1.14.13.63]
3-hydroxyphenylacetate + NAD(P)H + O(2) = 2,5-dihydroxyphenylacetate + NAD(P)(+) + H(2)O.
  • 3-hydroxyphenylacetate 6-hydroxylase from Flavobacterium sp. is highly specific for 3-hydroxyphenylacetate and uses NADH and NADPH as electron donors with similar efficiency.
1 Q078T0