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CATH Superfamily 1.10.630.10

Cytochrome P450

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 43: Cytochrome P450 99A2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(S)-limonene 6-monooxygenase. [EC: 1.14.14.51]
(S)-limonene + [reduced NADPH--hemoprotein reductase] + O(2) = (-)-trans- carveol + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • The enzyme participates in the biosynthesis of (-)-carvone, which is responsible for the aroma of spearmint.
  • Formerly EC 1.14.13.48.
 4 Q6WKZ1 Q6WKZ1 Q9XHE8 Q9XHE8
(S)-limonene 3-monooxygenase. [EC: 1.14.14.99]
(S)-limonene + [reduced NADPH--hemoprotein reductase] + O(2) = (-)-trans- isopiperitenol + [oxidized NADPH--hemoprotein reductase] + H(2)O.
  • A cytochrome P450 (heme-thiolate) protein from peppermint (Mentha piperita).
  • Formerly EC 1.14.13.47.
 4 Q6IV13 Q6WKY9 Q9XHE6 Q9XHE7
9-beta-pimara-7,15-diene oxidase. [EC: 1.14.14.111]
9-beta-pimara-7,15-diene + 3 O(2) + 3 [reduced NADPH--hemoprotein reductase] = 9-beta-pimara-7,15-dien-19-oate + 3 [oxidized NADPH- -hemoprotein reductase] + 4 H(2)O.
  • A cytochrome P450 (heme-thiolate) protein.
  • The enzyme from rice (Oryza sativa) is involved in the biosynthesis of the phytoalexin momilactone.
  • It also acts similarly on 9-beta-stemod-13(17)-ene.
  • Formerly EC 1.14.13.144.
 1 Q0JF01