The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cytochrome P450
".
FunFam 127: Cytochrome P450 Cyp124
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
|
10 | P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P9WPP2 (/ISS) |
|
Cholesterol 26-hydroxylase activity GO:0031073
Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol.
|
10 | P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P9WPP2 (/ISS) |
|
Cholest-4-en-3-one 26-monooxygenase activity GO:0036199
Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.
|
10 | P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P9WPP2 (/ISS) |
|
NADPH binding GO:0070402
Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
|
10 | P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P9WPP2 (/ISS) |
|
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
|
9 | P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) |
|
Cholesterol 26-hydroxylase activity GO:0031073
Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol.
|
9 | P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) |
|
Cholest-4-en-3-one 26-monooxygenase activity GO:0036199
Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.
|
9 | P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) |
|
NADPH binding GO:0070402
Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
|
9 | P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fatty acid omega-oxidation GO:0010430
A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.
|
10 | P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P9WPP2 (/ISS) |
|
Methyl-branched fatty acid metabolic process GO:0097089
The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.
|
10 | P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P0A517 (/ISS) P9WPP2 (/ISS) |
|
Fatty acid omega-oxidation GO:0010430
A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.
|
9 | P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) |
|
Methyl-branched fatty acid metabolic process GO:0097089
The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.
|
9 | P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) P9WPP3 (/IDA) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.