The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Farnesyl Diphosphate Synthase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Geranylgeranyl pyrophosphate synthase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Geranylgeranyl diphosphate synthase. [EC: 2.5.1.29]
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
  • Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.
41 A0A024R3W4 A0A024R3W4 A0A024R3W4 A0A024R3W4 A0A0B0E3G4 A0A0B0E3G4 A0A2R9AIF6 A0A2R9AIF6 A0A2R9AIF6 A0A2R9AIF6
(31 more...)
(2E,6E)-farnesyl diphosphate synthase. [EC: 2.5.1.10]
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)- farnesyl diphosphate.
  • Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate.
  • The enzyme will not accept larger prenyl diphosphates as efficient donors.
41 A0A024R3W4 A0A024R3W4 A0A024R3W4 A0A024R3W4 A0A0B0E3G4 A0A0B0E3G4 A0A2R9AIF6 A0A2R9AIF6 A0A2R9AIF6 A0A2R9AIF6
(31 more...)
Dimethylallyltranstransferase. [EC: 2.5.1.1]
Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
  • Will not accept larger prenyl diphosphates as efficient donors.
41 A0A024R3W4 A0A024R3W4 A0A024R3W4 A0A024R3W4 A0A0B0E3G4 A0A0B0E3G4 A0A2R9AIF6 A0A2R9AIF6 A0A2R9AIF6 A0A2R9AIF6
(31 more...)