The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Farnesyl Diphosphate Synthase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 44: (2Z,6E)-hedycaryol synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
4 B1W019 (/IDA) B1W019 (/IDA) B5GMG2 (/IDA) D5SL78 (/IDA)
Sesquiterpene synthase activity GO:0010334
Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons.
2 B1W019 (/IDA) B1W019 (/IDA)
Hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances GO:0016823
Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.
2 B1W019 (/IDA) B1W019 (/IDA)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
2 B1W019 (/IDA) B1W019 (/IDA)
Terpene synthase activity GO:0010333
Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.
1 E4MYY0 (/IDA)
Germacrene-A synthase activity GO:0034005
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.
1 B2J4A4 (/IDA)
R-linalool synthase activity GO:0034008
Catalysis of the reaction: geranyl diphosphate + H(2)O = (R)-linalool + diphosphate.
1 D5SL78 (/IDA)
Pentalenene synthase activity GO:0050467
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene.
1 Q82IY4 (/IDA)
1,8-cineole synthase activity GO:0102313
Catalysis of the reaction: geranyl diphosphate(3-) + H2O <=> 1,8-cineole + diphosphoric acid
1 B5GMG2 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sesquiterpene biosynthetic process GO:0051762
The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
3 B1W019 (/IDA) B1W019 (/IDA) B2J4A4 (/IDA)
Sesquiterpenoid biosynthetic process GO:0016106
The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.
2 B1W019 (/IDA) B1W019 (/IDA)
Geranyl diphosphate metabolic process GO:0033383
The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.
2 B5GMG2 (/IDA) D5SL78 (/IDA)
Antibiotic biosynthetic process GO:0017000
The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
1 Q82IY4 (/IDA)
Farnesyl diphosphate metabolic process GO:0045338
The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.
1 D5SL78 (/IDA)
Lactone biosynthetic process GO:1901336
The chemical reactions and pathways resulting in the formation of lactone.
1 Q82IY4 (/IDA)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.