The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 21: Serine/threonine protein kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
61 O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA)
(51 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
52 O34507 (/IPI) O34507 (/IPI) O34507 (/IPI) O34507 (/IPI) O34507 (/IPI) P9WI67 (/IPI) P9WI67 (/IPI) P9WI67 (/IPI) P9WI67 (/IPI) P9WI67 (/IPI)
(42 more)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
45 P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI71 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA)
(35 more)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
20 A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) Q81WH6 (/ISS)
(10 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
19 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
(9 more)
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
14 A6QGC0 (/IDA) A6QGC0 (/IDA) A6QGC0 (/IDA) A6QGC0 (/IDA) A6QGC0 (/IDA) A6QGC0 (/IDA) A6QGC0 (/IDA) A6QGC0 (/IDA) A6QGC0 (/IDA) O34507 (/IDA)
(4 more)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
11 P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP)
(1 more)
Acetyltransferase activator activity GO:0010698
Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.
11 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
(1 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
11 P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI) P9WI81 (/IPI)
(1 more)
Peptidoglycan binding GO:0042834
Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
11 Q81WH6 (/ISS) Q81WH6 (/ISS) Q81WH6 (/ISS) Q81WH6 (/ISS) Q81WH6 (/ISS) Q81WH6 (/ISS) Q81WH6 (/ISS) Q81WH6 (/ISS) Q81WH6 (/ISS) Q81WH6 (/ISS)
(1 more)
Nickel cation binding GO:0016151
Interacting selectively and non-covalently with nickel (Ni) cations.
9 P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
9 P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2 B0BD08 (/IMP) Q8NU97 (/IMP)
Transferase activity, transferring phosphorus-containing groups GO:0016772
Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
1 Q8NU97 (/IDA)

There are 32 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
46 P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA)
(36 more)
Negative regulation of fatty acid biosynthetic process GO:0045717
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
44 P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA)
(34 more)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
38 P9WI71 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA)
(28 more)
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
38 P9WI71 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA)
(28 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
23 O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA) P9WI77 (/IDA)
(13 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
20 A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) Q81WH6 (/ISS)
(10 more)
Positive regulation of DNA binding GO:0043388
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
20 P9WI71 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
(10 more)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
19 P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP)
(9 more)
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
19 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
(9 more)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
16 O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP)
(6 more)
Spore germination GO:0009847
The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).
16 O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP)
(6 more)
Cellular response to peptidoglycan GO:0071224
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
16 O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) O34507 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP) Q81WH6 (/IMP)
(6 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
11 P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP)
(1 more)
Peptidoglycan biosynthetic process GO:0009252
The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
11 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
(1 more)
Negative regulation of growth rate GO:0045967
Any process that reduces the rate of growth of all or part of an organism.
11 P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP) P9WI81 (/IMP)
(1 more)
Response to host immune response GO:0052572
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
11 P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA) P9WI81 (/IDA)
(1 more)
Response to nitrosative stress GO:0051409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
10 P9WI77 (/IMP) P9WI77 (/IMP) P9WI77 (/IMP) P9WI77 (/IMP) P9WI77 (/IMP) P9WI77 (/IMP) P9WI77 (/IMP) P9WI77 (/IMP) P9WI77 (/IMP) P9WI77 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
9 A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI)
Spore germination GO:0009847
The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).
9 A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI)
Cellular response to peptidoglycan GO:0071224
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
9 A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI) A6QGC0 (/IGI)
Energy homeostasis GO:0097009
Any process involved in the balance between food intake (energy input) and energy expenditure.
9 P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA) P9WI67 (/IDA)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
8 P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
8 P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)
Negative regulation of lipid biosynthetic process GO:0051055
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
8 P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA)
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
7 P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA) P9WI63 (/IDA)
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
2 Q9I758 (/IDA) Q9I758 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P9WI71 (/IMP)
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
1 P9WI71 (/IMP)
Regulation of lipid biosynthetic process GO:0046890
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
1 P9WI71 (/IMP)
Regulation of cell division GO:0051302
Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
1 Q8KY50 (/IMP)
Response to host immune response GO:0052572
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 P9WI71 (/IEP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
26 P9WI77 (/HDA) P9WI77 (/HDA) P9WI77 (/HDA) P9WI77 (/HDA) P9WI77 (/HDA) P9WI77 (/HDA) P9WI77 (/HDA) P9WI77 (/HDA) P9WI77 (/HDA) P9WI77 (/HDA)
(16 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
20 P9WI71 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI81 (/HDA)
(10 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
20 A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) A6QGC0 (/ISS) Q81WH6 (/ISS)
(10 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
16 P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI83 (/HDA) P9WI83 (/HDA)
(6 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
15 P9WI63 (/HDA) P9WI63 (/HDA) P9WI63 (/HDA) P9WI63 (/HDA) P9WI63 (/HDA) P9WI63 (/HDA) P9WI63 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA)
(5 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
13 O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) O34507 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA) P9WI83 (/IDA)
(3 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
8 P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P9WI71 (/IDA)