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CATH Superfamily 1.10.40.30

Fumarase/aspartase (C-terminal domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (C-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Aspartate ammonia-lyase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 135 P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI) P0AC38 (/IPI)
(125 more)
Aspartate ammonia-lyase activity GO:0008797
Catalysis of the reaction: L-aspartate = fumarate + NH3.
 135 P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA)
(125 more)
Aspartate ammonia-lyase activity GO:0008797
Catalysis of the reaction: L-aspartate = fumarate + NH3.
 7 Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aspartate metabolic process GO:0006531
The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
 134 P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA)
(124 more)
Cellular amino acid biosynthetic process GO:0008652
The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
 134 P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA)
(124 more)
Cellular amino acid metabolic process GO:0006520
The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
 7 Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS) Q9KNN3 (/ISS)
Positive regulation of plasminogen activation GO:0010756
Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
 1 P44324 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 134 P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA)
(124 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 134 P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA) P0AC38 (/IDA)
(124 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 134 P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA) P0AC38 (/HDA)
(124 more)