The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 38: Potassium voltage-gated channel subfamily KQT memb...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Voltage-gated cation channel activity GO:0022843
Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
11 A0A0B4KEH2 (/IDA) A0A0B4KEI9 (/IDA) A0A0B4KEP9 (/IDA) A0A0B4KF62 (/IDA) A0A0B4KFJ4 (/IDA) A1Z856 (/IDA) B7YZR3 (/IDA) B7YZR4 (/IDA) Q5PXF9 (/IDA) Q8IGU8 (/IDA)
(1 more)
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
2 G5EDN5 (/IDA) Q8MQC5 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
13 A0A0B4KEH2 (/IDA) A0A0B4KEI9 (/IDA) A0A0B4KEP9 (/IDA) A0A0B4KF62 (/IDA) A0A0B4KFJ4 (/IDA) A1Z856 (/IDA) B7YZR3 (/IDA) B7YZR4 (/IDA) G5EDN5 (/IDA) Q5PXF9 (/IDA)
(3 more)
Embryonic development via the syncytial blastoderm GO:0001700
The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
11 A0A0B4KEH2 (/IMP) A0A0B4KEI9 (/IMP) A0A0B4KEP9 (/IMP) A0A0B4KF62 (/IMP) A0A0B4KFJ4 (/IMP) A1Z856 (/IMP) B7YZR3 (/IMP) B7YZR4 (/IMP) Q5PXF9 (/IMP) Q8IGU8 (/IMP)
(1 more)
Regulation of heart rate GO:0002027
Any process that modulates the frequency or rate of heart contraction.
11 A0A0B4KEH2 (/IMP) A0A0B4KEI9 (/IMP) A0A0B4KEP9 (/IMP) A0A0B4KF62 (/IMP) A0A0B4KFJ4 (/IMP) A1Z856 (/IMP) B7YZR3 (/IMP) B7YZR4 (/IMP) Q5PXF9 (/IMP) Q8IGU8 (/IMP)
(1 more)
Cardiac muscle contraction GO:0060048
Muscle contraction of cardiac muscle tissue.
11 A0A0B4KEH2 (/IMP) A0A0B4KEI9 (/IMP) A0A0B4KEP9 (/IMP) A0A0B4KF62 (/IMP) A0A0B4KFJ4 (/IMP) A1Z856 (/IMP) B7YZR3 (/IMP) B7YZR4 (/IMP) Q5PXF9 (/IMP) Q8IGU8 (/IMP)
(1 more)
G protein-coupled acetylcholine receptor signaling pathway GO:0007213
Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
2 G5EDN5 (/IDA) Q8MQC5 (/IDA)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
2 G5EDN5 (/IDA) Q8MQC5 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
11 A0A0B4KEH2 (/IDA) A0A0B4KEI9 (/IDA) A0A0B4KEP9 (/IDA) A0A0B4KF62 (/IDA) A0A0B4KFJ4 (/IDA) A1Z856 (/IDA) B7YZR3 (/IDA) B7YZR4 (/IDA) Q5PXF9 (/IDA) Q8IGU8 (/IDA)
(1 more)