The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
lambda repressor-like DNA-binding domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 32: Transcriptional regulator ClgR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
13 P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA)
(3 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
13 P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA)
(3 more)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
5 Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
5 Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
5 Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
5 Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
5 Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
5 Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
13 P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP)
(3 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
13 P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP)
(3 more)
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
13 P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP)
(3 more)
Regulation of DNA-templated transcription in response to stress GO:0043620
Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
13 P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA)
(3 more)
Growth of symbiont in host cell GO:0044119
The increase in size or mass of symbiont, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
13 P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA)
(3 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
13 P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA)
(3 more)
Negative regulation by symbiont of host innate immune response GO:0052170
Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
13 P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA)
(3 more)
Regulation of proteasomal protein catabolic process GO:0061136
Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
13 P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP)
(3 more)
Dormancy exit of symbiont in host GO:0085016
Exit from dormant state, also known as resuscitation, of the symbiont within the host organism.
13 P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA) P9WMH7 (/IDA)
(3 more)
Regulation of trehalose metabolic process GO:0090062
Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
13 P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP) P9WMH7 (/IEP)
(3 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
5 Q8NP59 (/IEP) Q8NP59 (/IEP) Q8NP59 (/IEP) Q8NP59 (/IEP) Q8NP59 (/IEP)
DNA restriction-modification system GO:0009307
A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.
1 Q8E8A7 (/ISS)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
11 P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA) P9WMH9 (/HDA)
(1 more)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
5 Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP) Q8NP59 (/EXP)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
5 Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP) Q8NP59 (/IMP)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
5 Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI) Q8NP59 (/IPI)