The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

DsrC-like protein, C-terminal domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: DsrC protein, C-terminal domain

This superfamily includes TusE, a partner to TusBCD in a sulphur relay system for 2-thiouridine biosynthesis, a tRNA base modification process PMID:16387657. Other members are DsrC PMID:18829451, a functionally similar protein in species where the sulphur relay system exists primarily for sulphur metabolism PMID:22815818, rather than tRNA base modification. Some members of this superfamily are known explicitly as the gamma subunit of sulphite reductases.

This superfamily represents the C-terminal domain found in DsrC and TusE proteins. It consists of 4 alpha helices(INTERPRO:IPR042072) .

GO Diversity

Unique GO annotations
6 Unique GO terms

EC Diversity

Unique EC annotations
1 Unique EC terms

Species Diversity

Unique species annotations
2505 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 14
Domain clusters (>95% seq id): 6
Domain clusters (>35% seq id): 1
Unique PDBs: 8
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 4
Unique EC: 1
Unique GO: 6
Unique Species: 2505