The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 914: LuxR family transcriptional regulator

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
9 P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA)
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
9 P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
9 P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA)
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
9 P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
9 P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
9 P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
9 P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
9 P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
9 P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
9 P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
9 P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
9 P25084 (/IEP) P25084 (/IEP) P25084 (/IEP) P25084 (/IEP) P25084 (/IEP) P25084 (/IEP) P25084 (/IEP) P25084 (/IEP) P25084 (/IEP)
Positive regulation of elastin biosynthetic process GO:0051544
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.
9 P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP)
Regulation of elastin catabolic process GO:0060310
Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
9 P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
9 P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA) P25084 (/IDA)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
9 P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP) P25084 (/IMP)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
9 P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI) P25084 (/IPI)