CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 89: Alkaline phosphatase synthesis response regulator
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
|
36 |
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
(26 more) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
36 |
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
(26 more) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
5 | I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
5 | I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
5 | I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
5 | I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
5 | I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
5 | I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
|
36 |
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
(26 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
36 |
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
(26 more) |
|
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
|
36 |
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
A0A1J9VGT7 (/ISS)
(26 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
11 |
P37478 (/IMP)
P37478 (/IMP)
P37478 (/IMP)
P37478 (/IMP)
P37478 (/IMP)
P37478 (/IMP)
P37478 (/IMP)
P37478 (/IMP)
P37478 (/IMP)
P37478 (/IMP)
(1 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
8 | E0TZB5 (/IEP) E0TZB5 (/IEP) E0TZB5 (/IEP) E0TZB5 (/IEP) E0TZB5 (/IEP) E0TZB5 (/IEP) E0TZB5 (/IEP) E0TZB5 (/IEP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | I6L8Z5 (/EXP) I6L8Z5 (/EXP) I6L8Z5 (/EXP) I6L8Z5 (/EXP) I6L8Z5 (/EXP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | I6L8Z5 (/IEP) I6L8Z5 (/IEP) I6L8Z5 (/IEP) I6L8Z5 (/IEP) I6L8Z5 (/IEP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoid GO:0009295
The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.
|
8 | E0TZB5 (/IMP) E0TZB5 (/IMP) E0TZB5 (/IMP) E0TZB5 (/IMP) E0TZB5 (/IMP) E0TZB5 (/IMP) E0TZB5 (/IMP) E0TZB5 (/IMP) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
5 | I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) I6L8Z5 (/IDA) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
5 | I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) I6L8Z5 (/IMP) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
5 | I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) I6L8Z5 (/IPI) |