CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 358: Acetylserotonin O-methyltransferase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 12 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Acetylserotonin O-methyltransferase activity GO:0017096
Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
|
5 | B3GSH5 (/IDA) D3KU66 (/IDA) D3KU67 (/IDA) P46597 (/IDA) P46597 (/IDA) |
|
Acetylserotonin O-methyltransferase activity GO:0017096
Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
|
3 | P10950 (/ISS) Q8HZJ0 (/ISS) Q92056 (/ISS) |
|
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
|
2 | P46597 (/TAS) P46597 (/TAS) |
|
S-methyltransferase activity GO:0008172
Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.
|
2 | P46597 (/TAS) P46597 (/TAS) |
|
Acetylserotonin O-methyltransferase activity GO:0017096
Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
|
2 | D3KU66 (/IMP) D3KU67 (/IMP) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P46597 (/IPI) P46597 (/IPI) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | P46597 (/IPI) P46597 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O95671 (/IPI) |
|
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
|
1 | C0LTM6 (/IDA) |
|
O-methyltransferase activity GO:0008171
Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
|
1 | B4XY98 (/IDA) |
|
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
|
1 | B3GSH5 (/IDA) |
|
S-adenosyl-L-methionine binding GO:1904047
Interacting selectively and non-covalently with S-adenosyl-L-methionine.
|
1 | C0LTM6 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
5 | B3GSH5 (/IDA) D3KU66 (/IDA) D3KU67 (/IDA) P46597 (/IDA) P46597 (/IDA) |
|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
3 | P10950 (/ISS) Q8HZJ0 (/ISS) Q92056 (/ISS) |
|
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
|
2 | P46597 (/TAS) P46597 (/TAS) |
|
Melatonin biosynthetic process GO:0030187
The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
|
2 | D3KU66 (/IMP) D3KU67 (/IMP) |
|
Indolalkylamine biosynthetic process GO:0046219
The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
|
2 | P46597 (/TAS) P46597 (/TAS) |
|
Negative regulation of male gonad development GO:2000019
Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.
|
2 | D3KU66 (/IMP) D3KU67 (/IMP) |
|
Antibiotic biosynthetic process GO:0017000
The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
|
1 | B4XY98 (/IDA) |
|
Methylation GO:0032259
The process in which a methyl group is covalently attached to a molecule.
|
1 | B4XY98 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P46597 (/TAS) P46597 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O95671 (/IDA) |