CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1110 | Calcium-transporting ATPase, transmembrane domain |
|
1.20.1110.10 | Calcium-transporting ATPase, transmembrane domain |
Domain Context
CATH Clusters
| Superfamily | Calcium-transporting ATPase, transmembrane domain |
| Functional Family | Sodium/potassium-transporting ATPase subunit alpha |
Enzyme Information
| 7.2.2.19 |
H(+)/K(+)-exchanging ATPase.
based on mapping to UniProt P19156
ATP + H(2)O + H(+)[side 1] + K(+)[side 2] = ADP + phosphate + H(+)[side 2] + K(+)[side 1].
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- A gastric mucosal enzyme that catalyzes the efflux of one H(+) and the influx of one K(+) per ATP hydrolyzed. -!- Formerly EC 3.6.1.36 and EC 3.6.3.10.
|
UniProtKB Entries (1)
| P19156 |
ATP4A_PIG
Sus scrofa
Potassium-transporting ATPase alpha chain 1
|
PDB Structure
| PDB | 5YLV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of the gastric proton pump
Nature
|