CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Thymidylate kinase

Enzyme Information

2.7.4.9
dTMP kinase.
based on mapping to UniProt O67099
ATP + dTMP = ADP + dTDP.

UniProtKB Entries (1)

O67099
KTHY_AQUAE
Aquifex aeolicus VF5
Thymidylate kinase

PDB Structure

PDB 5XBH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate.
Biswas, A., Shukla, A., Chaudhary, S.K., Santhosh, R., Jeyakanthan, J., Sekar, K.
FEBS J.