CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.80 | Alpha-Beta Horseshoe | |
3.80.10 | Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) | |
3.80.10.10 | Ribonuclease Inhibitor |
Domain Context
CATH Clusters
Superfamily | Ribonuclease Inhibitor |
Functional Family | Toll-like receptor 7 |
Enzyme Information
UniProtKB Entries (1)
Q9NR97 |
TLR8_HUMAN
Homo sapiens
Toll-like receptor 8
|
PDB Structure
PDB | 5WYZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Small-molecule inhibition of TLR8 through stabilization of its resting state
Nat. Chem. Biol.
|