CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease Inhibitor
Functional Family Toll-like receptor 7

Enzyme Information

UniProtKB Entries (1)

Q9NR97
TLR8_HUMAN
Homo sapiens
Toll-like receptor 8

PDB Structure

PDB 5WYZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Small-molecule inhibition of TLR8 through stabilization of its resting state
Zhang, S., Hu, Z., Tanji, H., Jiang, S., Das, N., Li, J., Sakaniwa, K., Jin, J., Bian, Y., Ohto, U., Shimizu, T., Yin, H.
Nat. Chem. Biol.