CATH Domain 5v0eZ02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family	exonuclease 1

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt Q9UQ84

UniProtKB Entries (1)

EXO1_HUMAN

Homo sapiens

Exonuclease 1

PDB Structure

PDB	5V0E
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I. Shi, Y., Hellinga, H.W., Beese, L.S. Proc. Natl. Acad. Sci. U.S.A.