CATH Domain 5u1mA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Insulin receptor substrate 1

Enzyme Information

UniProtKB Entries (1)

INSR_HUMAN

Homo sapiens

Insulin receptor

PDB Structure

PDB	5U1M
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression. Cai, W., Sakaguchi, M., Kleinridders, A., Gonzalez-Del Pino, G., Dreyfuss, J.M., O'Neill, B.T., Ramirez, A.K., Pan, H., Winnay, J.N., Boucher, J., Eck, M.J., Kahn, C.R. Nat Commun