CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1260.10
Functional Family Non-heme ferritin

Enzyme Information

1.16.3.2
Bacterial non-heme ferritin.
based on mapping to UniProt P52093
4 Fe(2+) + O(2) + 6 H(2)O = 4 (FeO(OH)) + 8 H(+).
-!- Ferritins are intracellular iron-storage and detoxification proteins found in all kingdoms of life. -!- They are formed from two subunits that co-assemble in various ratios to form a spherical protein shell. -!- Thousands of mineralized iron atoms are stored within the core of the structure. -!- The product of dioxygen reduction by the bacterial non-heme ferritin is hydrogen peroxide, which is consumed in a subsequent reaction.

UniProtKB Entries (2)

P52093
FTN_HELPY
Helicobacter pylori 26695
Bacterial non-heme ferritin
Q51006
Q51006_NEIGO
Neisseria gonorrhoeae
MtrE protein

PDB Structure

PDB 5U1B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-based design of ferritin nanoparticle immunogens displaying antigenic loops of Neisseria gonorrhoeae.
Wang, L., Xing, D., Le Van, A., Jerse, A.E., Wang, S.
FEBS Open Bio