CATH Domain 5tmpA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Thymidylate kinase

Enzyme Information

2.7.4.9

dTMP kinase.

based on mapping to UniProt P0A720

ATP + dTMP = ADP + dTDP.

UniProtKB Entries (1)

KTHY_ECOLI

Escherichia coli K-12

Thymidylate kinase

PDB Structure

PDB	5TMP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase. Lavie, A., Ostermann, N., Brundiers, R., Goody, R.S., Reinstein, J., Konrad, M., Schlichting, I. Proc.Natl.Acad.Sci.USA