CATH Domain 5tc4A01

Note: The assignment for domain 5tc4A01 was not available when the latest CATH+ database (v4_3_0) was released. The information below comes from putative assignments made in our daily snapshot: CATH-B. These assignments have gone through fewer checks than information from a CATH+ release.

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily
Functional Family	-

PDB Structure

PDB	5TC4
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor. Gustafsson, R., Jemth, A.S., Gustafsson, N.M., Farnegardh, K., Loseva, O., Wiita, E., Bonagas, N., Dahllund, L., Llona-Minguez, S., Haggblad, M., Henriksson, M., Andersson, Y., Homan, E., Helleday, T., Stenmark, P. Cancer Res.