CATH Domain 5nufC02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.110	L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
	3.90.110.10	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family	Malate dehydrogenase

Enzyme Information

1.1.1.37

Malate dehydrogenase.

based on mapping to UniProt P93819

(S)-malate + NAD(+) = oxaloacetate + NADH.

-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

MDHC1_ARATH

Arabidopsis thaliana

Malate dehydrogenase 1, cytoplasmic

PDB Structure

PDB	5NUF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. Huang, J., Niazi, A.K., Young, D., Rosado, L.A., Vertommen, D., Bodra, N., Abdelgawwad, M.R., Vignols, F., Wei, B., Wahni, K., Bashandy, T., Bariat, L., Van Breusegem, F., Messens, J., Reichheld, J.P. J. Exp. Bot.