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CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Packaging enzyme P4

Enzyme Information

3.6.1.15
Nucleoside-triphosphate phosphatase.
based on mapping to UniProt P11125
NTP + H(2)O = NDP + phosphate.
-!- The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria. -!- Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD. -!- The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.

UniProtKB Entries (1)

P11125
P4_BPPH6
Pseudomonas virus phi6
Packaging enzyme P4

PDB Structure

PDB 5MUW
External Links
Method ELECTRON MICROSCOPY
Organism
Primary Citation
Double-stranded RNA virus outer shell assembly by bona fide domain-swapping.
Sun, Z., El Omari, K., Sun, X., Ilca, S.L., Kotecha, A., Stuart, D.I., Poranen, M.M., Huiskonen, J.T.
Nat Commun
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